Mentoring and research in patient-oriented medicine

描述（由申请人提供）：补充和替代医学（CAM）中以患者为导向的转化研究缺乏财政，机构和智力资源。下一代CAM研究人员将受益于经验丰富的职业中期临床研究人员的专门指导。这项提议的K24以患者为导向的研究中期研究者奖将为布鲁斯巴雷特医学博士提供受保护的时间，以稳定和扩大他的研究计划，并将指导延伸到初级CAM研究人员。巴雷特计划提交申请NCCAM的T32 NRSA机构研究培训补助金的下一个应用周期（由于2011年1月25日）。该机构培训补助金将允许在威斯康星州大学医学与公共卫生学院（UW SMPH）开发CAM目标研究培训计划。 巴雷特博士是UW SMPH的终身副教授，在研究，出版，教学和指导方面有着良好的记录。 他的K23职业发展补助金和随后的两个R01研究赠款来自NCCAM。他目前领导UW初级保健研究奖学金，由卫生资源和服务管理局的T32 NRSA资助的六个博士后培训职位。 拟议的K24和T32赠款将通过家庭医学部（DFM）管理。DFM和UW SMPH是同类部门和机构中最强大和最成功的部门之一。 巴雷特博士指导初级教师，博士后研究员，住院医师，医学生和研究生。Barrett博士的几位学员目前正在从事CAM研究。 巴雷特巩固和扩大他的指导计划，并制定和提交一份T32申请，用于在UW SMPH DFM进行CAM研究的机构培训计划。 结合现有的资源和声誉，这将吸引越来越多的最合格和有前途的未来CAM研究人员。 有了这笔赠款，巴雷特博士将进行实质性的培训机会，以发展他的知识，技能和经验，以提高他负责任地进行以患者为导向的翻译CAM研究的能力。 这项研究将建立在以前研究的基础上，特别是两项成功的NCCAM资助的R01研究。 拟议的具体研究的总体目标是研究临床相互作用对后续疾病结局的潜在影响。项目将包括：1）开发和验证现有录像临床行为的交互分析方法，2）创新的贝叶斯中介分析方法，以解释最近完成的R01研究的结果。 这项拟议的K24赠款将支持补充，替代和综合医学的研究计划，这是一个资金不足和代表性不足的医学研究领域，并将支持和促进下一代CAM研究人员的发展。 公共卫生相关性：这项以患者为导向的研究中期研究者奖将支持布鲁斯巴雷特医学博士在他的追求：1）为有前途的年轻研究人员提供专门的指导，对补充和替代医学感兴趣，2）扩大他的研究计划。提出的具体研究将扩大知识的性质和以病人为导向的临床互动的影响。

DESCRIPTION (provided by applicant): Patient-oriented translational research in complementary and alternative medicine (CAM) suffers from a lack of financial, institutional, and intellectual resources. The next generation of CAM researchers will benefit from the dedicated mentorship of experienced midcareer clinical investigators. This proposed K24 Midcareer Investigator Award in Patient-Oriented Research will provide Bruce Barrett MD PhD with protected time to stabilize and expand his research program, and to extend mentorship to junior CAM researchers. Dr. Barrett plans to submit an application to NCCAM for a T32 NRSA Institutional Research Training Grant for the next application cycle (due January 25, 2011). This institutional training grant will allow the development of a CAM-targeted research training program at the University of Wisconsin School of Medicine and Public Health (UW SMPH). Dr. Barrett is a tenured Associate Professor at the UW SMPH, with a strong record of research, publication, teaching and mentoring. His K23 career development grant and two subsequent R01 research grants came from NCCAM. He currently leads the UW Primary Care Research Fellowship, with six post-doctoral training positions funded by a T32 NRSA from the Health Resources and Services Administration. The proposed K24 and T32 grants would be administered through the Department of Family Medicine (DFM). DFM and UW SMPH are among strongest and most successful of comparable departments and institutions. Dr. Barrett mentors junior faculty, post-doctoral fellows, resident physician, medical students and graduate students. Several of Dr. Barrett's mentees are currently engaged in CAM research. Funding of this grant would allow Dr. Barrett to solidify and expand his mentoring program, and to develop and submit a T32 application for an institutional training program in CAM research at UW SMPH DFM. Combined with existing resources and reputation, this would attract an increasing pool of the most qualified and promising future CAM researchers. With this grant Dr. Barrett would undertake substantive training opportunities to develop his knowledge, skills, and experience to enhance his ability to responsibly conduct patient oriented translational CAM research. The proposed research will build upon findings from previous research, especially two successful NCCAM-funded R01 studies. The overarching goal of the proposed specific research is to study potential influences of clinical interaction on subsequent illness outcomes. Projects will include: 1) development and validation of an interaction analysis approach to existing videotaped clinical behaviors, and 2) an innovative Bayesian mediation analysis approach to explain findings of recently completed R01 research. This proposed K24 grant would support a program of research in complementary, alternative and integrative medicine, an under-funded and under-represented area of medical research, and would support and facilitate the development of the next generation of CAM researchers. PUBLIC HEALTH RELEVANCE: This Midcareer Investigator Award in Patient-Oriented Research will support Bruce Barrett MD PhD in his quest to: 1) provide dedicated mentoring to promising young researchers with interest in complementary and alternative medicine, and 2) expand his research program. The specific research proposed would expand knowledge regarding the nature and impact of patient-oriented clinical interaction.