Advancing Reproductive Health: Qualitative Methods & Interdisciplinary Mentorship

描述（由申请人提供）：这个职业中期研究者奖（K24）将提供受保护的时间，资源和结构，这将使我的研究生涯轨迹的进展，从主要关注艾滋病毒预防，到更广泛的性和生殖健康（SRH）背景下更广泛的预防概念化。此外，它将使我能够在以患者为导向的研究中使用混合方法进行全面的指导过程。我的职业发展目标是：1）将我的知识和专业知识从艾滋病毒预防扩展到对性健康和生殖健康的更具包容性的关注，2）推动扩大研究议程，以开发有效的性健康和生殖健康技术和干预措施，和3）通过指导研究员和初级研究人员以患者为导向，促进我在健康促进科学混合方法研究中的学术作用research.拟议的指导计划将使我能够投入必要的时间和精力，将一个全面的混合方法研究培训计划完全整合到我对初级研究人员的指导中。拟议的研究将为指导这些调查人员提供背景。结构化的导师计划将使我能够为对预防干预和治疗评估研究感兴趣的初级研究人员提供科学领导和深入的方法学培训。通过这种指导国家的科学混合方法，我将促进严格的健康促进研究在广泛的健康促进科学的行为。我的职业生涯中期发展计划将使我能够从事学习和研究活动，扩大我的知识基础和专业知识到SRH，并帮助我更好地了解SRH技术的用户体验，并确定影响使用的因素。关键是“可接受性。“然而，目前关于遵守和可接受性的概念未能充分阐明和说明使用和不使用的模式。我建议，一个新的使用模式，“有效使用”，是必需的，并建议进行纵向前瞻性混合方法研究，以阐明这一模式。“有效使用”的概念始于对最佳用户体验的内在需求。它认为，用户的积极体验驱动使用，并且由于使用是由这种积极体验维持的，因此更高的生物医学干预暴露（例如，活性成分），无论是用于预防还是治疗。与公共卫生的相关性：性健康和生殖健康是全球公共卫生的优先事项。提供最有可能使用的有效性健康和生殖健康技术，将对妇女健康产生最大影响。如果成功，有效使用模式将为妇女及其伴侣开发性健康和生殖健康技术提供一个新的范例，从而增加使用并改善性健康和生殖健康成果。 公共卫生相关性：这个K24奖将为我提供受保护的时间来进行混合方法研究，这将阐明性和生殖健康技术发展的新范式：具体到我的研究，我们开发具有最大使用可能性的技术的能力将对妇女的性和生殖健康产生最大的影响，这是全球公共卫生的优先事项。K24奖还将为实施全面的混合方法导师计划提供时间，以培养健康促进科学领域的新研究人员骨干

DESCRIPTION (provided by applicant): This midcareer investigator award (K24) will provide protected time, resources, and structure that will allow for a progression in my research career trajectory, from a primary focus on HIV prevention, to a more inclusive and extensive conceptualization of prevention in the broader context of sexual and reproductive health (SRH). Further, it will allow me to engage in a comprehensive process of mentorship in the use of mixed methodologies in patient-oriented research. My career development goals are to: 1) expand my knowledge and expertise from HIV prevention alone to a more inclusive focus on sexual and reproductive health, 2) advance an expanded research agenda into the development of effective sexual and reproductive health technologies and interventions, and 3) advance my scholarly role in the use of mixed methods research for health promotion sciences by mentoring fellows and junior investigators in patient oriented research. The proposed mentorship plan will allow me to dedicate the necessary time and effort to fully integrate a comprehensive mixed methods research training program into my mentoring of junior investigators. The proposed research will provide the context for mentoring those investigators. The structured mentorship program will allow me to provide scientific leadership and in-depth methodological training for junior investigators interested in prevention intervention and treatment evaluation research. Through this mentorship in state-of-the-science mixed methods, I will promote the conduct of rigorous health promotion research across a wide range of health promotion sciences. My midcareer development plan will allow me to pursue learning and research activities that broaden my knowledge base and expertise into SRH and help me to better understand user experiences with SRH technologies, and identify those factors that impact use. Critical to use is "acceptability." However, current conceptualizations of adherence and acceptability fail to fully articulate and account for patterns of use and non-use. I propose that a new model of use, "Effective Use," is required, and propose the conduct of a longitudinal prospective mixed methods study to articulate this model. The concept of "Effective Use" begins with an inherent demand for the best user experience. It holds that a user's positive experience drives use, and that because use is maintained by this positive experience, higher exposure to the biomedical intervention (e.g., active ingredient), whether for prevention or treatment, is achieved. Relevance to Public Health: Sexual and reproductive health is a global public health priority. Providing efficacious SRH technologies that have the greatest likelihood of use will have the greatest impact on women's health. If successful, an Effective Use model would offer a new paradigm for the development of sexual and reproductive health technologies for women and their partners that will result in increased use and improved sexual and reproductive health outcomes. PUBLIC HEALTH RELEVANCE: This K24 award will provide me with protected time to conduct mixed methods research that will articulate a new paradigm for the development of sexual and reproductive health technologies: specific to my research, our ability to develop technologies that have the greatest likelihood of use will have the greatest impact on women's sexual and reproductive health, a global public health priority. The K24 award will also allow time to implement a comprehensive mixed methods mentorship program to train a new cadre of researchers in the health promotion sciences