2012 Cellular and Molecular Fungal Biology Gordon Research Conference

2012细胞与分子真菌生物学戈登研究会议

• 批准号: 8317251
• 负责人: Judith G. Berman
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-15 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8317251
• 关键词: Address; Animal Model; Animals; Area; Aspergillosis; Biology; Candidiasis; Cellular biology; Communities; Cryptococcus neoformans infection; Disease; Effectiveness; Evaluation; Gene Expression; Genomics; Goals; Health; Histoplasmosis; Human; Infection; Infection prevention; International; Modeling; Molecular; Mycoses; National Institute of Allergy and Infectious Disease; National Institute of General Medical Sciences; Oral; Organism; Participant; Pathogenesis; Plants; Population; Prevention; Process; RNA; Request for Proposals; Research; Research Personnel; Role; Schools; Symbiosis; Systems Biology; Therapeutic; Transplant Recipients; United States National Institutes of Health; design; distraction; fungus; human disease; interest; meetings; neglect; posters; symposium

DESCRIPTION (provided by applicant): This proposal requests partial support for the Gordon Research Conference on Cellular and Molecular Fungal Biology to be held at the Holderness School, June 17-22, 2012. The broad and long-term goal of the conference is to spread information about fungal biology among researchers to increase our collective understanding of basic fungal biology and its application to socially important problems. Fungi are excellent eukaryotic model organisms, so much of the conference will be central to the aims of NIH-National Institute of General Medical Science. Furthermore, fungi cause significant human disease, so much of the research presented will also address the interests of the NIH-National Institute of Allergy and Infectious Disease. The specific aim of this meeting will be to convene 52 speakers who represent the leading edge of fungal research with a total of ca. 130-140 participants, most of whom will present posters, for a five-day conference in a setting with few distractions. The oral and poster sessions are designed to emphasize discussion and networking, and evaluations from past conferences demonstrate the effectiveness of this format. The 2012 meeting will combine both newer and core topics to this conference such as systems biology, population and evolutionary genomics, pathogenesis, symbiosis, cell biology and gene expression including RNA control. The significance of this application is the demonstrated effect of this conference in accelerating research in the international fungal biology community, including prevention and treatment of disease. The health relatedness of this application centers on the role of fungi in human disease, including three of the most important diseases of transplant patients, candidiasis, cryptococcosis and aspergillosis, as well as systemic fungal diseases such as histoplasmosis. PUBLIC HEALTH RELEVANCE: Project Narrative: The health relatedness of this application concerns both the role that fungi play in human disease and the role that fungi play in understanding the fundamental features of eukaryotic biology. Knowledge of the biology of fungi is essential to the prevention of fungal disease by illuminating basic features of fungal development, and is essential to treatment of fungal disease by identifying targets for pharmaceuticals and molecular candidates for vaccines. Use of fungi as model organisms continues to speed our understanding of essential features of all complex life, including humans, through study of basic cellular and molecular processes.

描述（由申请人提供）：本提案要求对细胞和分子真菌生物学戈登研究会议将于2012年6月17日至22日在霍洛维茨学校举行的部分支持。会议的广泛和长期目标是在研究人员中传播有关真菌生物学的信息，以增加我们对基础真菌生物学及其在社会重要问题中的应用的集体理解。真菌是优秀的真核生物模式生物，因此会议的大部分内容将是NIH-国家普通医学科学研究所的核心目标。此外，真菌会导致严重的人类疾病，因此所提出的许多研究也将解决NIH-国家过敏和传染病研究所的利益。本次会议的具体目标是召开52次会议， 发言者谁代表真菌研究的前沿与总ca。130-140名与会者，其中大多数将提交海报，在一个几乎没有干扰的环境中举行为期五天的会议。口头会议和海报会议旨在强调讨论和建立联系，对以往会议的评价表明了这种形式的有效性。2012年的会议将联合收割机结合更新和核心的主题，如系统生物学，人口和进化基因组学，发病机制，共生，细胞生物学和基因表达，包括RNA控制。这一应用的重要性在于，本次会议在加速国际真菌生物学界的研究，包括疾病的预防和治疗方面发挥了示范作用。这种应用的健康相关性集中在真菌在人类疾病中的作用，包括移植患者的三种最重要的疾病，念珠菌病，隐球菌病和曲霉病，以及系统性真菌疾病，如组织胞浆菌病。 公共卫生关系：项目叙述：该应用的健康相关性涉及真菌在人类疾病中的作用以及真菌在理解真核生物学的基本特征中的作用。了解真菌的生物学对于通过阐明真菌发育的基本特征来预防真菌疾病是必不可少的，并且对于通过鉴定药物的靶标和疫苗的分子候选物来治疗真菌疾病是必不可少的。使用真菌作为模式生物，通过研究基本的细胞和分子过程，继续加速我们对所有复杂生命（包括人类）的基本特征的理解。