Core B: Facility/Service Cores

核心 B：设施/服务核心

• 批准号: 8322585
• 负责人: David Albert Schwartz
• 金额: $ 11.99万
• 依托单位: NATIONAL JEWISH HEALTH
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8322585
• 关键词: Altitude; Animals; Calibration; Child; Cultured Cells; Disease; Ensure; Health; In Vitro; Laboratory Personnel; Maintenance; Mammalian Cell; Monitor; Ozone; Ramp; Research Personnel; Rodent; Services; Site; System; Writing; computerized; data acquisition; follower of religion Jewish; in vivo; meetings; programs

Core Description: This Core will operate the exposure systems developed at National Jewish for the short-term exposures of cultured cells and rodents to physiologically relevant levels of ozone. In addition, the Core will respond to investigator requests for alterations of the systems to meet specific experimental requirements (e;g., ramping of ozone concentrations, correction of ozone concentration for altitude dilution effects, rocking of cultured cells). An important function of the Core will be to ensure that the ozone is confined to the experimental apparatus, thereby not endangering laboratory personnel. The Core also maintains the computerized data acquisition systems associated with the exposure units and modifies the internally written programs to meet invesfigator needs.

核心描述： 该核心将运行国家犹太人公司为短期曝光而开发的曝光系统 培养的细胞和啮齿动物达到生理上相关的臭氧水平。此外，核心将对 研究人员要求对系统进行更改以满足特定的实验要求(例如，坡道 臭氧浓度的变化，臭氧浓度对海拔稀释效应的修正，培养物的摇摆 单元格)。核心的一个重要功能将是确保臭氧被限制在实验中 仪器，从而不会危及实验室人员。核心还维护计算机化的数据 与曝光单元相关联的采集系统，并修改内部编写的程序以满足 投资方需要。