树突状细胞定向 T 细胞负调节治疗自身免疫-猫眼课题宝

树突状细胞定向 T 细胞负调节治疗自身免疫

批准号：

8334865

负责人：

CHENTHAMARAKSHAN VASU

金额：

$32.86万

依托单位：

MEDICAL UNIVERSITY OF SOUTH CAROLINA

依托单位国家：

美国

项目类别：

财政年份：

2009

资助国家：

美国

项目状态：

已结题

起止时间：

2009-02-24 至 2014-01-31

来源：

https://reporter.nih.gov/project-details/8334865

关键词：

Adopted Adverse effects Affinity Anti-Inflammatory Agents Anti-inflammatory Antigen Presentation Antigens Attention Autoimmune Diseases Autoimmune Process Autoimmune thyroiditis Autoimmunity Binding Bone Marrow CD28 gene CD4 Positive T Lymphocytes CD80 gene CDR1 gene Cell Communication Cell Differentiation process Cell physiology Cells Characteristics Clinical Complementary DNA Complex Cytotoxic T-Lymphocyte-Associated Protein 4 Dendritic Cells Disease Disease model Down-Regulation Effectiveness Engineering Event Future Generations Goals Graft Rejection Hashimoto Disease Homeostasis Immune Immune System Diseases Immunization Immunosuppressive Agents In Vitro Inbred NOD Mice Individual Inflammatory Response Pathway Insulin-Dependent Diabetes Mellitus Interleukin-10 Knock-in Mouse Lead Length Life Ligands Ligation Light Longevity Mediating Memory Methods Modeling Monitor Mus Nature Opportunistic Infections Orphan Ovalbumin Pathway interactions Peptides Physiologic pulse Process Property Receptor Activation Regulation Regulatory T-Lymphocyte Reporting Rest Risk Role Safety Signal Transduction Specificity Staging Stem cells Surface Synapses System T cell differentiation T cell response T-Cell Activation T-Cell Receptor T-Lymphocyte Testing Therapeutic Therapeutic Effect Therapeutic Studies Therapeutic Uses Thyroglobulin Time Tissues Transgenic Mice Wild Type Mouse cellular engineering cost effective cytokine experience high voltage electron microscopy in vitro testing in vivo inhibitor/antagonist interest mouse model mutant overexpression prevent public health relevance receptor receptor expression research study response tool

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