Restoration of Fecal Continence in Aging IAS

老年 IAS 患者大便失禁的恢复

• 批准号: 8368311
• 负责人: KHALIL N BITAR
• 金额: $ 30.82万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-02-01 至 2013-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8368311
• 关键词: 3-Dimensional; Acetylcholine; Actins; Adrenergic Agents; Adult; Affect; Age; Aging; Aliquot; Antibodies; Anus; Applications Grants; Area; Biomedical Engineering; Budgets; Canis familiaris; Caveolae; Caveolins; Cell Aging; Cells; Circular layer of muscularis propria of anal canal; Colon; Complementary DNA; Complex; Constipation; Contractile Proteins; Contracts; Cyclic AMP; Cytoskeletal Modeling; Cytoskeleton; Data; Development; Dominant-Negative Mutation; Dose; Down-Regulation; Elderly; Enteric Nervous System; Exhibits; Extravasation; Fecal Incontinence; Feces; Figs - dietary; Functional disorder; Gastrointestinal Contents; Gastrointestinal Sphincter; Generations; HSPB1 gene; Hand; Hormonal; Human; In Vitro; Interphase Cell; Investigation; Lead; Length; Lipids; Maintenance; Mechanics; Mediator of activation protein; Membrane; Membrane Microdomains; Methods; Modeling; Molecular; Motor; Movement; Muscle; Muscle Cells; Muscle Contraction; Muscle function; Nature; Nerve; Neurotransmitters; Outcome; Phosphorylation; Physiological; Play; Principal Investigator; Property; Protein Isoforms; Quality of life; Rattus; Rectum; Relaxation; Rest; Role; Signal Transduction; Skeletal Muscle; Smooth Muscle; Smooth Muscle Myocytes; Sphincter; Sucrose; Time; Tissue Engineering; Work; adrenergic; age effect; age related; aged; caveolin 1; cell age; cholinergic; cost; density; in vitro Model; in vivo; loss of function; novel; overexpression; pressure; programs; research study; response; restoration