Cancer Cell Adaptation to Hypoxia and/or Nutrient Deprivation
Cancer Cell Adaptation to Hypoxia and/or Nutrient Deprivation
批准号:
8327680
负责人:
CRAIG B THOMPSON
金额:
$35.59万
依托单位国家:
美国
项目类别:
财政年份:
2004
资助国家:
美国
项目状态:
未结题
起止时间:
2004-09-10 至
关键词:
5&apos-AMP-activated protein kinaseATP Synthesis PathwayAmino AcidsAntithymoglobulinApoptosisApoptoticAutophagocytosisBioenergeticsBiological PreservationCatabolismCell DeathCell HypoxiaCell LineCell ProliferationCell SurvivalCellsCollaborationsERBB2 geneElectron TransportEnzymesFatty AcidsFutile CyclingGenesGenetic TranscriptionGlucoseGlutamineGlycolysisGoalsGrowthHumanHydroxylationHypoxiaIncidenceInvestigationLaboratoriesLeadLeftLipidsLow Density Lipoprotein ReceptorMaintenanceMalignant - descriptorMalignant NeoplasmsMalonyl Coenzyme AMessenger RNAMetabolicMetabolic PathwayMetabolic stressMetabolismMitochondriaMolecularMouse Mammary Tumor VirusMusNatural regenerationNeoplasm MetastasisNormal CellNutrientOxidative PhosphorylationOxygenPathway interactionsPharmaceutical PreparationsPhospholipidsPhosphotransferasesPhysiologicalPhysiologyPolyunsaturated Fatty AcidsProductionProliferatingProlineProtein BiosynthesisProteinsPyruvateReagentRecoveryRecyclingReducing AgentsRegulationRelative (related person)ReportingRiskRoleSLC2A1 geneSignal TransductionStressSupplementationTSC2 geneTherapeuticTranscriptional ActivationTransgenesTransgenic AnimalsTransgenic OrganismsTranslationsTumorigenicityVascular SystemWorkXenograft procedureaerobic glycolysisanaerobic glycolysisbasecancer cellcancer therapycell growthcell transformationdeprivationdesignexperienceextracellularfatty acid oxidationglucose metabolismglucose uptakeinhibitor/antagonistinsightlactate dehydrogenase Alipid metabolismneoplastic cellnoveloxidationpromoterprotein complexreceptor expressionresearch studyresponsesmall hairpin RNAsuccesstumoruptake
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