MURINE MODELS CORE

小鼠模型已被华盛顿大学消化疾病研究所广泛使用 核心中心研究人员，是DDRCC炎症性肠病生物医学研究的核心， 消化系统的其他方面。小鼠模型核心一直并将继续致力于 生产转基因动物，并及时为DDRCC研究人员提供gnotobiotic小鼠 可靠的方式。此外，核心还提供了维护小鼠谱系的辅助服务，例如 如胚胎的辅助生殖和冷冻保存，以及突变或转基因的快速转移 从一个基因背景到另一个基因背景。我们将继续提供这些服务， 下一个项目周期。

Murine models have been extensively utilized by Washington University Digestive Diseases Research Core Center investigators and are central to DDRCC biomedical research into inflammatory bowel disease and other aspects of the digestive system. The Murine Models Core has been and will continue to be dedicated to producing genetically altered animals and to providing gnotobiotic mice for DDRCC investigators in a timely and reliable manner. In addition, the Core provides ancillary sen/ices for maintaining mouse pedigrees, such as assisted reproduction and cryopreservation of embryos, as well as rapid transfer of mutations or transgenes from one genetic background to another using "speed congenics". We will continue to offer these services in the next project period.