Administrative Core

行政核心 组织行政核心是为了利用大学的机构研究优势， 罗切斯特（UR），并利用UR的临床和转化科学研究所（CTSI）。主 行政核心的使命将是支持参与D-CFAR成员的研究方案， 并促进新的研究互动和项目。行政核心将通过以下方式履行其使命： 监督整个D-CFAR和新项目的建立;支持必要的职能 为D-CFAR的日常职能（通过组织和财政监督）提供支持; 全面的D-CFAR战略规划流程;与内部和外部咨询机构互动 董事会将提供重要的指导和建议。行政核心还将为以下方面提供支助： 项目评估和交流（包括一个专门的网站，以及科学研讨会和 它将创建一个共享的生物信息学资源，旨在为所有D-CFAR成员提供服务。这 资源将协调和整合现有的临床数据库和数据文件到共享的虚拟数据 它还将调整一般通信和数据收集的系统和标准; 增强受试者招募的工具;实施行为干预策略;促进 与南非的调查人员合作;并提供分析工具和软件， 基于实验室的研究。定期进行内部和外部审查，并结合全面的 衡量具体目标和成果的计划，将确保每一个D-CFAR倡议， 取得预期的进展。总的来说，行政核心将提供成功实现以下目标所需的“粘合剂”： 将D-CFAR的各个组成部分与关键的机构中心和计划相结合， 确保它达到成功转换为完整CFAR奖励所需的进度水平。

ADMINISTRATIVE CORE A. The Administrative Core has been organized to exploit institutional research strengths at the University of Rochester (UR), and to leverage the UR's Clinical and Translational Science Institute (CTSI). The primary mission of Administrative Core will be to support the research programs of participating D-CFAR members, and to facilitate new research interactions and projects. The Administrative Core will fulfill its mission by: overseeing the entire D-CFAR and the establishment of new programs; supporting the functions necessary for the day-to-day function of the D-CFAR (through organizational and fiscal oversight); providing a comprehensive D-CFAR strategic planning process; and interacting with internal and external advisory boards that will provide crucial guidance and advice. The Administrative core will also provide support for program evaluation and communications (including a dedicated web site, as well as scientific seminars and meetings), and it will create a shared Bioinformatics resource, designed to serve all D-CFAR members. This resource will coordinate and integrate existing clinical databases and data files into a shared virtual data repository; it will also adapt systems and standards for general communication and data collection; develop tools that enhance subject recruitment; implement strategies for delivery of behavioral interventions; facilitate collaboration with investigators in South Africa; and provide analytical tools and software to support laboratory-based studies. A process of regular internal and external review, combined with a comprehensive plan for measurement of specific objectives and outcomes, will ensure that each of the D-CFAR initiatives makes desired progress. Overall, the Administrative Core will provide the "glue" required to successfully integrate the various components of this D-CFAR with key institutional centers and programs, and to make sure that it achieves a level of progress necessary for successful conversion to a full CFAR award.