Ethical, Legal, and Social Implications in Military Genomics

描述（由申请人提供）：基因组科学的进步正在吸引美国军方的兴趣，因为它们有可能改善军队成员的医疗保健，并有助于军队招募，培训和专业化，以及使命的完成。此外，军方运营的大型DNA库可能是军事和民用研究人员的宝贵资源。虽然ELSI的研究项目已经探讨了在各种各样的情况下使用基因组科学提出的问题，有几乎没有检查的伦理，法律的，和军事基因组学提出的社会问题，超出了那些有关国防部（DoD）DNA登记的法医使用。该项目将带来来自ELSI计划的见解和更广泛的关于基因组科学所带来的伦理、法律的和社会问题的讨论，以应对军事上基因组科学潜在用途所带来的独特挑战。在目前正在进行的为军事生物增强制定生物伦理框架的基础上，本项目将构建第一个军事基因组学的生物伦理和法律的框架，并将利用该框架分析如何解决ELSI问题。 公共卫生相关性：该项目将为军事基因组学构建一个伦理和法律的框架，并将该框架应用于美国军方考虑使用的基因组科学。这将促进公共健康， 在法律上适当的方式来构建和利用拟议的新的军事/VA DNA生物库，并提供建议，如何保护军队及其家庭成员的健康和福祉，因为军队增加了基因组学的使用。

DESCRIPTION (provided by applicant): Advances in genomic science are attracting the interest of the U.S. military for their potential to improve medical care for members of the militay and to aid in military recruitment, training and specialization, and mission accomplishment. In addition, large DNA banks operated by the military could be a valuable resource for military and civilian researchers. While ELSI research projects have explored issues raised by the use of genomic science in a wide variety of contexts, there has been virtually no examination of the ethical, legal, and social issues raised by military genomics beyond those relating to forensic use of the Department of Defense (DoD) DNA Registry. This project will bring the insights from the ELSI program and the broader conversation on the ethical, legal, and social issues posed by genomic science in general to bear on the unique challenges presented by potential uses of genomic science by the military. Building on work now underway to develop a bioethical framework for military bioenhancement, this project will construct the first bioethical and legal framework for military genomics, and will employ this framework to analyze how ELSI issues might be resolved. PUBLIC HEALTH RELEVANCE: This project will construct an ethical and legal framework for military genomics and apply this framework would apply to uses of genomic science contemplated by the U.S. military. This will promote the public health by elucidating ethically and legally appropriate ways to construct and utilize a proposed new military/VA DNA biobank, and by offering suggestions for how to protect the health and well-being of members of the military and their families as the military increases its uses of genomics.