APPLICABILITY OF BOLD FMRI AT 3T AND 7T VISION & PERCEPTION

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， NCRR赠款不直接向子项目或子项目工作人员提供资金。 我们正在使用的视觉刺激范式，产生良好的特征化的本地化的神经抑制在初级视觉皮层测试是否，在一个良好的空间尺度上，积极的BOLD响应更密切相关的神经输出或本地的神经抑制。在过去的一年中，我们已经发表了一篇论文，证明V1 BOLD反应与局部神经抑制的幅度比与局部神经输出的相关性更好;第二篇手稿正在准备中。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We are using a visual stimulus paradigm that produces well-characterized localized neural inhibition in primary visual cortex to test whether, on a fine spatial scale, the positive BOLD response is more closely related to the neural output or the local neural inhibition. In the past year we have published one paper demonstrating that the V1 BOLD response correlates better with the magnitude of the local neural inhibition than with the local neural output; a second manuscript is in preparation.