Improving Kidney Transplant Outcomes Using Normothermic Machine Perfusion

捐赠用于移植的肾脏有损坏的风险，使器官无法工作，并缩短其寿命。常温机器灌流是一种设备，可以在移植前通过供体肾脏在正常体温下循环含氧血液。通过这样做，它能够复苏肾脏，防止受伤。我们将确定机器灌流是如何达到这种显著效果的，并研究治疗肾损伤的新方法。

Kidneys donated for transplantation are at risk of damage that prevent the organ from working and reduce its lifespan. Normothermic machine perfusion is a device that can circulate oxygenated blood at normal body temperature through a donor kidney prior to transplantation. In doing so it is able to resuscitate the kidney and prevent injury. We will determine how machine perfusion achieves this remarkable effect and investigate new treatments for kidney injury.