Increasing HPV Vaccine Uptake in a Low Income Ethnic Minority Population

提高低收入少数族裔人群对 HPV 疫苗的接种率

基本信息

  • 批准号:
    8464669
  • 负责人:
  • 金额:
    $ 54.42万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2012
  • 资助国家:
    美国
  • 起止时间:
    2012-05-01 至 2017-03-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Cervical cancer incidence in Los Angeles County is significantly higher than the national average, with highest rates among Latinas and Asian/Pacific Islanders. The discovery of HPV as the primary causal agent in cervical cancer and subsequent development of HPV vaccines have revolutionized the potential for cervical cancer prevention. However, vaccine utilization rates in the US remain unacceptably low among age-eligible girls, including among the highest risk groups. The UCLA School of Public Health & Jonsson Comprehensive Cancer Center have teamed with the Los Angeles County Department of Public Health, Office of Women's Health (OWH) to address the unequal burden of cervical cancer in Los Angeles. The primary goal of the study is to evaluate, in a randomized trial, a theoretically driven, culturally sensitive and individually tailored intervention to increase HPV vaccine receipt among underserved, high risk girls in Los Angeles. The intervention will be delivered via the existing OWH telephone education and service referral hotline in six languages (English, Spanish, Cantonese, Mandarin, Korean, Armenian). The multi-component intervention, directed at mothers of age-eligible girls (11-18 years), will consist of a brief telephone intervention that will deliver basic HPV vaccine information, individually tailored messages to address callers' barriers to HPV vaccination, and tailored referral to a clinic offering low cost/free vaccine. A tailored print intervention reinforcing the telephone messages will also be mailed to participants. The control group will receive usual care and a standard CDC fact sheet on the HPV vaccine. The primary outcome will be vaccine initiation among age-eligible girls (receipt of at least one vaccine dose) assessed at a 3 month telephone follow-up with mothers. A 9 month follow-up will assess vaccine completion rates (receipt of 3-dose series) and overall patterns of vaccine dose initiation and completion. The study also seeks to characterize HPV related knowledge, beliefs and barriers in the target population, and understand the mediators (e.g., knowledge, barriers reduction) through which the intervention may have achieved its desired effect. Differential effects of the intervention on subgroups of the sample (e.g., more acculturated) will also be assessed. The study is innovative in that we are partnering with the county health system which is the only realistic source of health care for our target population. The commitment of the county department of public health to increasing HPV vaccine uptake and the utilization of existing county infrastructure (the OWH hotline) for intervention delivery will ensure institutionalization of the intervention upon trial completion.
描述(由申请人提供):洛杉矶县的宫颈癌发病率明显高于全国平均水平,拉丁裔和亚洲/太平洋岛民的发病率最高。HPV作为宫颈癌主要致病因子的发现以及随后HPV疫苗的开发彻底改变了宫颈癌预防的潜力。然而,美国适龄女孩的疫苗使用率仍然低得令人无法接受,包括最高风险群体。加州大学洛杉矶分校公共卫生学院和琼森综合癌症中心与洛杉矶县公共卫生部妇女健康办公室(OWH)合作,以解决洛杉矶宫颈癌的不平等负担。该研究的主要目标是在一项随机试验中评估一种理论驱动的,文化敏感的和个性化的干预措施,以增加洛杉矶服务不足的高危女孩的HPV疫苗接种。干预措施将通过OWH现有的电话教育和服务转介热线以六种语言(英语、西班牙语、广东话、普通话、韩语、亚美尼亚语)提供。针对适龄女孩(11-18岁)的母亲的多组分干预将包括简短的电话干预,提供基本的HPV疫苗信息,个性化定制的信息,以解决呼叫者对HPV疫苗接种的障碍,并有针对性地转诊到提供低成本/免费疫苗的诊所。还将向与会者邮寄一份专门印刷的发言稿,以加强电话信息。对照组将接受常规护理和关于HPV疫苗的标准CDC情况说明书。主要结果将是在与母亲进行3个月电话随访时评估的年龄合格女孩(至少接受一剂疫苗)中的疫苗启动情况。9个月随访将评估疫苗完成率(接受3剂系列)和疫苗剂量开始和完成的总体模式。该研究还试图描述目标人群中HPV相关知识、信念和障碍的特征,并了解介导因素(例如,知识,减少障碍),通过这些措施可以达到预期的效果。干预措施对样本亚组的不同影响(例如,文化上的差异也将被评估。这项研究是创新的,因为我们正在与县卫生系统合作,这是我们目标人群唯一现实的卫生保健来源。县公共卫生部门致力于增加HPV疫苗的接种和利用现有的县基础设施(OWH热线)进行干预,这将确保在试验完成后将干预措施制度化。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Roshan Bastani其他文献

Roshan Bastani的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Roshan Bastani', 18)}}的其他基金

Addressing Obesity in Early Care and Education Settings
在早期护理和教育环境中解决肥胖问题
  • 批准号:
    10430160
  • 财政年份:
    2018
  • 资助金额:
    $ 54.42万
  • 项目类别:
Addressing Obesity in Early Care and Education Settings
在早期护理和教育环境中解决肥胖问题
  • 批准号:
    10163226
  • 财政年份:
    2018
  • 资助金额:
    $ 54.42万
  • 项目类别:
Addressing Obesity in Early Care and Education Settings
在早期护理和教育环境中解决肥胖问题
  • 批准号:
    9752319
  • 财政年份:
    2018
  • 资助金额:
    $ 54.42万
  • 项目类别:
Increasing HPV Vaccine Uptake in a Low Income Ethnic Minority Population
提高低收入少数族裔人群对 HPV 疫苗的接种率
  • 批准号:
    8831606
  • 财政年份:
    2012
  • 资助金额:
    $ 54.42万
  • 项目类别:
UCLA HEALTHY-BY-DEFAULT (HBD) REACH PROJECT
加州大学洛杉矶分校健康默认 (HBD) REACH 项目
  • 批准号:
    8525891
  • 财政年份:
    2012
  • 资助金额:
    $ 54.42万
  • 项目类别:
Increasing HPV Vaccine Uptake in a Low Income Ethnic Minority Population
提高低收入少数族裔人群对 HPV 疫苗的接种率
  • 批准号:
    9322599
  • 财政年份:
    2012
  • 资助金额:
    $ 54.42万
  • 项目类别:
Increasing HPV Vaccine Uptake in a Low Income Ethnic Minority Population
提高低收入少数族裔人群对 HPV 疫苗的接种率
  • 批准号:
    8239244
  • 财政年份:
    2012
  • 资助金额:
    $ 54.42万
  • 项目类别:
UCLA HEALTHY-BY-DEFAULT (HBD) REACH PROJECT
加州大学洛杉矶分校健康默认 (HBD) REACH 项目
  • 批准号:
    8728355
  • 财政年份:
    2012
  • 资助金额:
    $ 54.42万
  • 项目类别:
Increasing HPV Vaccine Uptake in a Low Income Ethnic Minority Population
提高低收入少数族裔人群对 HPV 疫苗的接种率
  • 批准号:
    8634738
  • 财政年份:
    2012
  • 资助金额:
    $ 54.42万
  • 项目类别:
UCLA/RAND PREVENTION RESEARCH CENTER
加州大学洛杉矶分校/兰德预防研究中心
  • 批准号:
    8337189
  • 财政年份:
    2009
  • 资助金额:
    $ 54.42万
  • 项目类别:

相似海外基金

Hormone therapy, age of menopause, previous parity, and APOE genotype affect cognition in aging humans.
激素治疗、绝经年龄、既往产次和 APOE 基因型会影响老年人的认知。
  • 批准号:
    495182
  • 财政年份:
    2023
  • 资助金额:
    $ 54.42万
  • 项目类别:
Investigating how alternative splicing processes affect cartilage biology from development to old age
研究选择性剪接过程如何影响从发育到老年的软骨生物学
  • 批准号:
    2601817
  • 财政年份:
    2021
  • 资助金额:
    $ 54.42万
  • 项目类别:
    Studentship
RAPID: Coronavirus Risk Communication: How Age and Communication Format Affect Risk Perception and Behaviors
RAPID:冠状病毒风险沟通:年龄和沟通方式如何影响风险认知和行为
  • 批准号:
    2029039
  • 财政年份:
    2020
  • 资助金额:
    $ 54.42万
  • 项目类别:
    Standard Grant
Neighborhood and Parent Variables Affect Low-Income Preschool Age Child Physical Activity
社区和家长变量影响低收入学龄前儿童的身体活动
  • 批准号:
    9888417
  • 财政年份:
    2019
  • 资助金额:
    $ 54.42万
  • 项目类别:
The affect of Age related hearing loss for cognitive function
年龄相关性听力损失对认知功能的影响
  • 批准号:
    17K11318
  • 财政年份:
    2017
  • 资助金额:
    $ 54.42万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Affect regulation and Beta Amyloid: Maturational Factors in Aging and Age-Related Pathology
影响调节和 β 淀粉样蛋白:衰老和年龄相关病理学中的成熟因素
  • 批准号:
    10166936
  • 财政年份:
    2017
  • 资助金额:
    $ 54.42万
  • 项目类别:
Affect regulation and Beta Amyloid: Maturational Factors in Aging and Age-Related Pathology
影响调节和 β 淀粉样蛋白:衰老和年龄相关病理学中的成熟因素
  • 批准号:
    9320090
  • 财政年份:
    2017
  • 资助金额:
    $ 54.42万
  • 项目类别:
Affect regulation and Beta Amyloid: Maturational Factors in Aging and Age-Related Pathology
影响调节和 β 淀粉样蛋白:衰老和年龄相关病理学中的成熟因素
  • 批准号:
    9761593
  • 财政年份:
    2017
  • 资助金额:
    $ 54.42万
  • 项目类别:
How age dependent molecular changes in T follicular helper cells affect their function
滤泡辅助 T 细胞的年龄依赖性分子变化如何影响其功能
  • 批准号:
    BB/M50306X/1
  • 财政年份:
    2014
  • 资助金额:
    $ 54.42万
  • 项目类别:
    Training Grant
Inflamm-aging: What do we know about the effect of inflammation on HIV treatment and disease as we age, and how does this affect our search for a Cure?
炎症衰老:随着年龄的增长,我们对炎症对艾滋病毒治疗和疾病的影响了解多少?这对我们寻找治愈方法有何影响?
  • 批准号:
    288272
  • 财政年份:
    2013
  • 资助金额:
    $ 54.42万
  • 项目类别:
    Miscellaneous Programs
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了