Systematic Review Core (SRC)/Ian D. Coulter

核心描述该核心，即系统综述核心（SRC），将对4个项目进行所有系统综述（SR）和文献综述。这些审查范围从项目1基于临床医生的适当性的全面系统性审查和可能的荟萃分析到项目2、3和4的不太广泛的审查，我们预计无法进行荟萃分析。这些审查将由Samueli研究所的一个专家小组与位于兰德公司的南加州循证实践中心（SCEPC）合作进行。Samueli研究所已经开发了一个强大的，高效的和严格的过程进行系统性评价，并进行了审查，几乎所有的主要类别的CAM [1-15]使用的过程被称为快速证据评估的文献或真实的过程。简单地说，Samueli研究所已经在一个名为Mobius Analytics的基于网络的平台上实现了审查过程的自动化，系统性审查系统SRS（版权所有2003-2009 Mobius Analytics Inc.，渥太华，安大略）以提高该过程的效率。真实的过程的一个关键优势是，Samueli研究所开发了一个系统，不仅可以在查看质量时评估内部有效性，还可以评估外部有效性和模型有效性标准。这一过程是作为一个简化的系统评价系统而开发的，它更加客观和基于标准，提高了评价者在评价过程中的可靠性，并创建了一个模型，能够以比大多数系统评价更快的方式以更低的成本生成证据报告。 SCEPC是美国进行SR的首要中心之一。它在CAM中进行了许多以前的审查。SCEPC之前获得了NCCAM的三年赠款，通过AHRQ管理，为CAM提供技术专业知识和进行系统审查。SCEPC与 过去曾与Samueli研究所合作进行过几次系统评价。

Core Description This Core, the Systematic Review Core (SRC) will conduct all the systematic reviews (SRs) and literature reviews for the 4 Projects. These will range from a full systematic review and possible meta-analysis for Project 1 Clinician Based Appropriateness to less extensive reviews for Projects 2,3 and 4 where we are not anticipating being able to conduct meta-analysis. The reviews will be conducted by an expert team at the Samueli Institute with cooperation ofthe Southern California Evidence-Based Practice Center (SCEPC) located at the RAND Corporation. The Samueli Institute has developed a robust, efficient and rigorous process for conducting systematic reviews and has conducted reviews in almost all the major categories of CAM [1-15] using a process referred to as the Rapid Evidence Assessment ofthe Literature or REAL¿ process. Briefly, Samueli Institute has automated the review process on a web-based platform known as Mobius Analytics, Systematic Review System SRS (Copyright 2003-2009 Mobius Analytics Inc., Ottawa, Ontario) to increase the efficiency of the process. A key advantage of the REAL process is that Samueli Institute has developed a system to not only assess internal validity when looking at quality but also external validity and model validity criteria. This process has been developed as a streamlined systematic review system that is more objective and criteria-based, increasing inter-rater reliability in the review process and creating a model that is able to produce evidence reports in a more rapid fashion at a reduced cost than most systematic reviews. The SCEPC is one ofthe premier centers for conducting SRs in the US. It has conducting numerous previous reviews in CAM. The SCEPC was previously awarded a three year grant from NCCAM, administered through AHRQ, to provide technical expertise and conduct systematic reviews for CAM. The SCEPC has collaborated with Samueli Institute on several systematic reviews in the past.