Improving Stroke Outcomes: Attenuating Progression and Recurrence

改善中风结果：减缓进展和复发

• 批准号: nhmrc : 1013612
• 负责人: Prof David Howells
• 金额: $ 622.26万
• 依托单位国家: 澳大利亚
• 项目类别: Program Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/improving-stroke-outcomes-progression-recurrence/109732
• 关键词: Improving; Stroke; Outcomes; Attenuating; Progression

Stroke is the second most common cause of death and major cause disability. There are few proven interventions, so we need to introduce new ones. We developed a bench to bedside program to introduce new stroke therapies and its early secondary prevention. Our general goal is to provide evidence for their effectiveness and safety. We will use animal stroke models, markers in the blood to help diagnose and predict stroke outcome and imaging to help select patients for several clinical trials.

中风是导致死亡和残疾的第二常见原因。行之有效的干预措施很少，因此我们需要引入新的干预措施。我们开发了一个从实验室到临床的计划，以引入新的中风疗法及其早期二级预防。我们的总体目标是为其有效性和安全性提供证据。我们将使用动物中风模型、血液中的标记物来帮助诊断和预测中风结果，并使用影像学来帮助选择患者进行多项临床试验。