Administrative

行政的

• 批准号: 8516872
• 负责人: Eric Hunter
• 金额: $ 44.63万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2016-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8516872
• 关键词: AIDS Vaccines; Acquired Immunodeficiency Syndrome; Advisory Committees; Animals; Annual Reports; Antibodies; Avidity; B-Lymphocytes; Binding; Budgets; Cellular biology; Communication; Consultations; Cytotoxic T-Lymphocytes; DNA; DNA Vaccines; DNA/MVA vaccine; Data; Data Analyses; Data Base Management; Databases; Decision Making; Development; Dose; Ensure; Epidemic; Goals; Granulocyte-Macrophage Colony-Stimulating Factor; HIV; HIV Envelope Protein gp120; Immune; Immune response; Immunization; Immunoglobulin A; Immunology; Individual; Institution; Instruction; Intellectual Property; Leadership; Legal patent; Macaca; Mediation; Peptide Vaccines; Peptides; Production; Proteins; Publications; Publishing; Reagent; Research; Research Personnel; Research Project Grants; Resources; SIV; Sampling; Science; Specimen; T cell response; T-Lymphocyte; Teleconferences; Tissue Sample; United States National Institutes of Health; Vaccines; Viral; Virus; base; data management; data sharing; meetings; neutralizing antibody; nonhuman primate; operation; programs; rectal; repository; response; success; transmission process; vaccine development

The Administrative Core will provide overall leadership and coordination for the Consortium. Through its specimen repository and database management functions, it will ensure that there is a coordinated and efficient utilization of non-human primate samples derived from projects 1, 2 and 3. It will be responsible for collecting, storing and analyzing samples from the individual Research Programs and Cores within the Consortium, and will provide statistical support for data analysis, in order to ensure that effective and functional collaborative science results. The Administrative Core will maintain budgets and oversee any rebudgeting that may be needed to meet Consortium goals. The Core, in conjunction with the individual investigators and an external advisory committee, will ensure that established research milestones are met. It will organize monthly investigator meetings and teleconferences to ensure that regular opportunities for communication between the scientific components ofthe Consortium are established. It will organize the production and procurement of DNA and MVA vaccine components, as well as coordinate SIV peptide acquisition from the NIH AIDS Repository for individual research projects and cores. The Core will provide logistical support for timely sharing of data internally and externally through publications and presentations according to the Data Sharing Plan, and manage intellectual filings and MTAs as well as co-ordinate the distribution of unique resources under appropriate MTAs. Overall, the Administrative Core will provide the

行政核心将为该财团提供全面领导和协调。通过其标本库和数据库管理功能，它将确保协调和有效地利用来自项目1、2和3的非人类灵长类动物样本。它将负责收集、储存和分析来自联盟内各个研究项目和核心的样本，并将为数据分析提供统计支持，以确保有效和功能性的合作科学成果。行政核心将维持预算并监督可能需要满足财团目标的任何重新预算。核心将与个别研究人员和外部咨询委员会共同确保达到既定的研究里程碑。它将组织每月的研究者会议和电话会议，以确保在联盟的科学组成部分之间建立定期的沟通机会。它将组织DNA和MVA疫苗成分的生产和采购，并协调从美国国立卫生研究院艾滋病知识库获取SIV肽，用于个人研究项目和核心。核心将根据《数据共享计划》，通过出版物和介绍，为及时在内部和外部共享数据提供后勤支持，管理知识文件和多边贸易协定，并协调在适当的多边贸易协定下分配独特资源。总的来说，行政核心将提供