Aging and the immune system

描述（由申请人提供）：此R-13申请寻求对将于2013年8月22日至27日在米兰举行的国际免疫学大会（ICI）的卫星会议“衰老和免疫系统”的部分支持。这次会议将汇集来自世界各地的科学家，包括美国和欧洲的科学家，他们的智力重点是衰老的免疫学。 本次会议将于2013年8月20日和21日在米兰举行。在此，我们请求提供资金，以便美国的发言者能够参加会议。 计划中的会议将提供一个很好的场所，就衰老免疫系统研究的最新成就，基因组学的优势和局限性进行建设性讨论，包括 微生物组，以及该领域的方法学发展和临床应用，来自 制药公司和疫苗开发。我们期望这次会议将大大有助于 一个更加一体化和更好地协调欧洲和美国的研究结构在免疫老年学。 此外，我们认为，这次会议，特别是反对伊斯兰会议组织的会议，将吸引新的调查人员和受训人员到实地。本次会议将加强现有的合作，并支持创建新的翻译研究，这将有利于老龄化人口。米兰会议中心MiCo是欧洲最大的会议设施，于2011年开业，位于米兰市中心，因此可以方便地乘坐地铁，并完全无障碍。 会议的第一个目标是总结衰老免疫学研究的最新进展， 最重要的研究领域，如适应性免疫学、先天免疫学和临床应用免疫学。 第二个目标是引发对《公约》的优点、局限性和潜在问题的批判性讨论， 将这些发现应用于未来更好地帮助老年人的干预措施（疫苗）。最近 疫苗的开发，预测反应性的生物标志物，以及最近发现的干预措施， 讨论 第三个目标是设计未来的战略：（a）如何优化互动、联网和协作 （B）如何组织欧美之间持续交流 科学家 从历史上看，美国的免疫学和衰老的重点一直是鼠系统，而在欧洲主要是人类。这次会议将允许更好的互动，不仅是两个不同的地理，而且学科组，并将作出实质性的贡献，进一步加强免疫老年学作为一个独特的，普遍接受的领域内的基础免疫学。

DESCRIPTION (provided by applicant): This R-13 application seeks partial support for a Satellite Meeting "Aging and the Immune System" in conjunction with the International Congress of Immunology (ICI) to be held in Milan, August 22-27, 2013. This meeting will bring together scientists from all over the world including American and European scientists whose intellectual focus is the immunology of aging. This conference, will take place in Milan on August 20th and 21st, 2013. Here we request funds to allow participation by speakers from the United States. The planned conference will provide an excellent venue for constructive discussions on recent achievements in research on the aging immune system, advantages and limits of the usage of genomics, including the microbiome, as well as methodological development and clinical application in this field, participation from pharmaceutical companies and vaccine development. We expect that this meeting will significantly contribute to a more integrated and better-coordinated European and American research structure in immunogerontology. In addition, we believe that the meeting, particularly with its opposition to the ICI, will attract ne investigators and trainees to the field. This meeting will enforce already existing collaborations and support the creation of new translational studies which will benefit the aging human population. The venue, the Milan Congress Center, MiCo, is the largest conference facility in Europe, opened in 2011, located in downtown Milan and therefore easily accessible by Metrorail and fully handicap accessible. First goal of the meeting is to summarize recent progress in research on immunology of aging, addressing the most important research areas such as adaptive, innate and clinically applied immunology. The second goal is to trigger a critical discussion on the advantages, limits and potential problems of the application of these discoveries to future interventions which can better help the elderly (vaccines). Recent vaccine development, biomarkers to predict responsiveness, and recently discovered interventions will be discussed. The third goal is to design future strategies on (a) how to optimize interaction, networking and collaborations in this specific research field, and (b) how to organize continuous interchange between European and US scientists. Historically, the focus of immunology and aging in the US has been with murine systems, whereas in Europe has mainly been with humans. This meeting will allow better interaction not only of the 2 different geographical but also disciplinary groups, and will make a substantial contribution to further strengthen immunogerontology as a distinct, generally accepted field within basic immunology.