Add Health Parent Study: Phase I

描述(由申请人提供)：此应用程序启动关于添加健康家长研究(添加健康-PS)的第一阶段数据收集。Add Health-PS是一个创新项目，其中一个跨学科的科学家团队将收集和分析社会、 国家青少年健康纵向研究(ADD Health)成员父母的行为和生物学数据。Add Health-PS将利用原始的Add Health受访者的丰富纵向数据，首次捕获关于两个相关世代的生物、基因和社会数据。这些独特的数据将支持研究三个实质性领域的代际联系：(I)健康、功能和健康行为；(Ii)认知功能、人格特征和偏好；以及(Iii)家庭支持、关系质量和义务纽带。为了实现这一科学目标，数据收集和Add Health-PS从以下四个具体目标开始：1)样本选择和地点：选择、跟踪和定位ADD Health受访者的总共5,000名父母的样本，其中包括16年前在Add Health第一波中与其青春期孩子一起接受采访的3,125名父母(主要是母亲)，以及预计在第一波中与该父母住在一起的1,875名“第二父母”(主要是父亲)，他们在第一波中出现在Add Health家庭中，但当时没有被采访。2)设计调查和生物标记物收集：开发一个60分钟的CAPI/CASI调查仪器，在笔记本电脑上管理，30分钟收集物理测量和生物标本的协议，以及记录在访谈中获得的空间数据并对其进行地理编码的程序。仪器开发和生物标志物的选择将由一个强大的跨学科设计团队指导，该团队将制定必要的措施，以满足上述研究的科学目标。3)现场调查和收集生物标志物：对我们目标样本中的每一位ADD Health父母进行90分钟的面谈，在此期间收集以下数据：调查数据、人体测量数据、来自血斑和唾液样本的生物数据和血压监测仪、来自DNA的基因数据以及空间数据的地理位置。我们计划收集在过去和计划中的未来Add Health浪潮中收集的关于它们后代的相同生物标记物、认知、个性和相关评估。这项实地工作将在该项目的五年内展开。4)数据管理、传播和标本存档：在现场工作期间实时监测数据质量以排除故障，清理和记录调查数据和生物标记方案，准备和传播数据以增加Health-PS调查人员和Add Health用户的科学社区，并维护生物标本存档以供未来测试。

DESCRIPTION (provided by applicant): This application launches the first phase of data collection on the Add Health Parent Study (Add Health-PS). The Add Health-PS is an innovative project in which an interdisciplinary team of scientists will gather and analyze social, behavioral, and biological data on the parents of the members of the National Longitudinal Study of Adolescent Health (Add Health). Add Health-PS will leverage the rich longitudinal data on the original Add Health respondents to capture, for the first time, biological, genetic and social data on two linked generations. These unique set of data will support the study intergenerational linkages in three substantive domains: (i) health, functionality, and health behaviors; (ii) cognitive functioning, personality traits and preferences; and (iii) family suppor, relationship quality and ties of obligation. To address this scientific objective, data collection n Add Health-PS begins with these four Specific Aims: 1) Sample Selection & Location: Select, trace and locate a total sample of 5,000 parents of Add Health respondents, consisting of a random sample of 3,125 parents (mainly mothers) who were interviewed 16 years ago with their adolescent child in the Wave I of Add Health and an anticipated 1,875 "2nd parents" (mainly fathers) who currently live with that Wave I parent, were present in the household Add Health household at Wave I, but were not interviewed at that time. 2) Design Survey & Biomarker Collection: Develop a 60-minute CAPI/CASI survey instrument to be administered on a laptop computer, protocols for a 30-minute collection of physical measurements and biological specimens, and procedures to record and geocode spatial data obtained at the interview. Instrument development and choice of biomarkers will be guided by a strong interdisciplinary Design Team that will produce needed measures to address the scientific objectives for research noted above. 3) Field Survey & Collect Biomarkers: Conduct a 90-minute in-person interview with each Add Health parent in our target sample during which the following data are collected: survey data, anthropometric data, biological data from blood spot and saliva specimens and a blood pressure monitor, genetic data from DNA, and geographic locations for spatial data. We plan to collect the same biomarkers, cognitive, personality and related assessments that were collected on their offspring in past and planned future waves of Add Health. This field work will be spread over the five years of the project. 4) Data Management, Dissemination & Specimen Archiving: Monitor data quality during fieldwork to trouble-shoot in real time, clean and document survey data and biomarker protocols, prepare and disseminate data to Add Health-PS investigators and the scientific community of Add Health users, and maintain a bio- logical specimen archive for future testing.