Add Health Parent Study: Phase I

描述（由申请人提供）：该应用程序启动Add Health父研究（Add Health-PS）的第一阶段数据收集。 添加健康PS是一个创新的项目，其中一个跨学科的科学家团队将收集和分析社会， 行为和生物学数据的成员的父母的国家青少年健康纵向研究（添加健康）。Add Health-PS将利用原始Add Health受访者的丰富纵向数据，首次捕获两代人的生物，遗传和社会数据。 这些独特的数据集将支持研究代际联系在三个实质性领域：（i）健康，功能和健康行为;（ii）认知功能，人格特质和偏好;（iii）家庭支持，关系质量和义务关系。为了实现这一科学目标，数据收集从以下四个具体目标开始：1）样本选择和位置：选择、追踪和定位总共5,000名Add Health受访者的父母样本，其中包括3名随机样本，125位家长（主要是母亲）谁采访了16年前与他们的青春期孩子在第一波添加健康和预期的1，目前与第一波父母一起生活的875名“第二父母”（主要是父亲）在第一波时出现在家庭添加健康家庭中，但当时没有接受采访。 2)设计调查和生物标志物收集：开发一个60分钟的CAPI/CASI调查工具，在笔记本电脑上管理，30分钟收集物理测量和生物标本的协议，以及记录和地理编码采访时获得的空间数据的程序。仪器开发和生物标志物的选择将由强大的跨学科设计团队指导，该团队将制定必要的措施来解决上述研究的科学目标。 3)实地调查和收集生物标志物：对我们目标样本中的每位Add Health家长进行90分钟的面对面访谈，在此期间收集以下数据：调查数据，人体测量数据，来自血斑和唾液标本的生物数据以及血压监测仪，来自DNA的遗传数据以及空间数据的地理位置。我们计划收集与过去收集的后代相同的生物标志物，认知，个性和相关评估，并计划未来的Add Health浪潮。这一实地工作将在项目的五年期间进行。 4)数据管理、传播和标本采集：在现场工作期间监测数据质量，以便真实的及时排除故障，清理和记录调查数据和生物标志物协议，准备和传播数据给Add Health-PS调查人员和Add Health用户的科学界，并维护生物学标本档案，以供未来测试。

DESCRIPTION (provided by applicant): This application launches the first phase of data collection on the Add Health Parent Study (Add Health-PS). The Add Health-PS is an innovative project in which an interdisciplinary team of scientists will gather and analyze social, behavioral, and biological data on the parents of the members of the National Longitudinal Study of Adolescent Health (Add Health). Add Health-PS will leverage the rich longitudinal data on the original Add Health respondents to capture, for the first time, biological, genetic and social data on two linked generations. These unique set of data will support the study intergenerational linkages in three substantive domains: (i) health, functionality, and health behaviors; (ii) cognitive functioning, personality traits and preferences; and (iii) family suppor, relationship quality and ties of obligation. To address this scientific objective, data collection n Add Health-PS begins with these four Specific Aims: 1) Sample Selection & Location: Select, trace and locate a total sample of 5,000 parents of Add Health respondents, consisting of a random sample of 3,125 parents (mainly mothers) who were interviewed 16 years ago with their adolescent child in the Wave I of Add Health and an anticipated 1,875 "2nd parents" (mainly fathers) who currently live with that Wave I parent, were present in the household Add Health household at Wave I, but were not interviewed at that time. 2) Design Survey & Biomarker Collection: Develop a 60-minute CAPI/CASI survey instrument to be administered on a laptop computer, protocols for a 30-minute collection of physical measurements and biological specimens, and procedures to record and geocode spatial data obtained at the interview. Instrument development and choice of biomarkers will be guided by a strong interdisciplinary Design Team that will produce needed measures to address the scientific objectives for research noted above. 3) Field Survey & Collect Biomarkers: Conduct a 90-minute in-person interview with each Add Health parent in our target sample during which the following data are collected: survey data, anthropometric data, biological data from blood spot and saliva specimens and a blood pressure monitor, genetic data from DNA, and geographic locations for spatial data. We plan to collect the same biomarkers, cognitive, personality and related assessments that were collected on their offspring in past and planned future waves of Add Health. This field work will be spread over the five years of the project. 4) Data Management, Dissemination & Specimen Archiving: Monitor data quality during fieldwork to trouble-shoot in real time, clean and document survey data and biomarker protocols, prepare and disseminate data to Add Health-PS investigators and the scientific community of Add Health users, and maintain a bio- logical specimen archive for future testing.