Training in Neurostatistics and Neuroepidemiology

这是对2004年在哈佛公共卫生学院(HSPH)发起的神经统计学和神经流行病学培训计划的继续支持的请求。这笔赠款将通过生物统计部进行管理。它将包括经验丰富的多学科培训人员的积极参与，包括HSPH的11名初级培训师和附属哈佛医院的23名二级培训师。这些教员在HSPH和哈佛医学院的生物统计学和流行病学系有预约。拟议的培训计划旨在满足神经疾病研究中的两个迫切需求：需要训练有素、了解并致力于神经科学和神经病学研究的生物统计学家，以及需要训练有素、了解并致力于使用定量研究方法的神经学家。为了满足这些关键需求，这笔赠款建议培训三名生物统计学博士后和一名博士后，以及两名流行病学博士后。生物统计学学员将在与神经疾病研究相关的领域发展方法论专业知识，包括生存分析、纵向研究、临床试验、功能磁共振成像分析和遗传学研究，以及在几种神经疾病及其伴随的测量和分析技术方面的实质性专业知识。流行病学实习生将是神经学(或相关领域)方面的高资质MD专家。这些受训人员将发展流行病学和生物统计学方法方面的专业知识，使他们能够在临床和转化性神经疾病研究方面追求成功的学术生涯。学员将在该计划中度过至少两年的时间。该计划将利用HSPH生物统计学和流行病学方法培训的强大传统，以及哈佛大学在神经疾病研究方面丰富多样的资源。学员将完成生物统计学和流行病学方法的课程，他们将积极参与合作研究体验，包括通过哈佛神经发现中心提供的许多机会。

This is a request for continuation of support for a training program in Neurostatistics and Neuroepidemiology launched in 2004 at the Harvard School of Public Health (HSPH). The Grant will be administered through the Department of Biostatistics. It will involve active participation by an accomplished, experienced, and multidisciplinary training faculty, including 11 primary trainers at HSPH and 23 secondary trainers at the affiliated Harvard hospitals. These faculty members have appointments at the Departments of Biostatistics and Epidemiology at HSPH and at Harvard Medical School. The proposed training program aims to serve two pressing needs in neurologic diseases research: the need for well-trained biostatisticians who have an understanding of and commitment to research in neuroscience and neurology and the need for highly trained neurologists who have an understanding of and commitment to utilization of quantitative research methods. To serve these critical needs, this grant proposes to train three pre-doctoral students and one post-doctoral student in biostatistics and two post-doctoral students in epidemiology. The biostatistics trainees will develop methodologic expertise in areas relevant to neurologic diseases research, including survival analysis, longitudinal studies, clinical trials, fMRI analysis, and genetic studies, and substantive expertise in several neurologic diseases and their accompanying measurement and analysis techniques. The epidemiology trainees will be highly qualified MD specialists in neurology (or related field). These trainees will develop expertise in epidemiologic and biostatistical methods, enabling them to pursue successful academic careers in clinical and translational neurologic diseases research. Trainees will spend a minimum of two years in the Program. The Program will capitalize on the strong tradition of training in biostatistical and epidemiologic methods at HSPH and on the rich and varied resources in neurologic diseases research available at Harvard. Trainees will complete coursework in biostatistical and epidemiologic methods and they will actively engage in collaborative research experiences, including many opportunities offered through the Harvard NeuroDiscovery Center.