Clinical and Transtional Science Institute

我们在加州大学旧金山分校成立了加州大学旧金山分校临床和翻译科学研究所(CTSI) 2006年，加州大学旧金山分校(UCSF)加快了改善公众健康的研究步伐。CTSI的总体使命一直是改善和转变加州大学旧金山分校及其合作机构的临床和转化性研究基础设施和培训。在下一个资助期，我们的目标是利用我们开发的大量知识、技能和基础设施，进一步加快加州大学旧金山分校的研究步伐，将我们的成功输出到其他机构，并通过以下目标创建旨在改善我们自己和其他社区健康的倡议： 具体目标1：加强加州大学旧金山分校CTSI非常成功的活动，包括开发新的 培训、基础设施/服务和宣传/文化变革领域的举措：a)培训：提供 面向所有级别的学生的计划，涵盖各种设置，并包括 医疗保健；b)基础设施/服务：将服务和工具扩展到加州大学旧金山分校、我们的合作机构以及更广泛的区域、国家和全球社区的临床和翻译研究人员；以及，c)倡导/文化变革：培养交流、鼓励合作、促进创新，并催化成功地进行临床和翻译研究；支持多样化的教师队伍；增加社区的参与和研究对其需求的响应；以及改变学术文化，以促进多学科、协作的工作。 具体目标2：使用由开发的知识、技能和基础设施开发横切计划 在第一个资助期实施多个CTSI计划，以加快临床和转化性研究及其对 健康，远远超出加州大学旧金山分校CTSI的合作机构。新的倡议将：a)将当地公众聚集在一起 健康和慈善团体与CTSI合作，改善旧金山湾区社区的健康 通过一系列针对高影响条件的健康改善项目；b)创建示范系统，以 加快临床和转化性研究的步伐，包括精简监管、开发参与者招募服务、提供研究管理，并将研究服务直接纳入社区实践；以及(C)通过设定具有挑战性的目标并在公共仪表盘上跟踪绩效指标，提高CTSI内部和Jeyond CTSI内部研究管理的绩效、透明度和问责制。 这些目标将通过协调我们10个项目内部和之间发生的活动来实现，并得到成熟的治理模式的支持，并与机构和社区领导层建立牢固的联系。我们的最终目标是更快地为更多人带来更好的健康。

We established the UCSF Clinical and Translational Science Institute (CTSI) at the University of California, San Francisco (UCSF) in 2006 to accelerate the pace of research that improves the health ofthe public. The overall mission of CTSI has been to improve and transform clinical and translational research infrastructure and training at UCSF and our partner institutions. In the next funding period we aim to use the substantial knowledge, skills, and infrastructure that we have developed to further accelerate the pace of research at UCSF, to export our successes to other institutions, and to create initiatives aimed at improving the health of our own and other communities, through the following aims: SPECIFIC AIM 1: To enhance the highly successful activities of the UCSF CTSI, including the development of new initiatives in the areas of Training, Jnfrastructure/Services, and Advocacy/Culture Change: a) Training: to provide programs for students at all levels, across a spectrum of settings, and including all phases of the improvement of healthcare; b) Infrastructure/Services: to expand services and tools to clinical and translational investigators at UCSF, our partner institutions, and within the broader regional, national, and global communities; and, c) Advocacy/Culture Change: to nurture communication, encourage collaboration, foster innovation, and catalyze the successful conduct of clinical and translational research; to support a diverse faculty; to increase involvement ofthe community and the responsive of research to its needs; and change the academic culture to promote multidisciplinary, collaborative work. SPECIFIC AIM 2: To develop crosscutting initiatives using the knowledge, skills, and infrastructure developed by multiple CTSI programs in the first funding period to accelerate clinical and translational research and its impact on health, well beyond the institutions collaborating in the UCSF CTSI. New initiatives will: a) Bring together local public health and philanthropic groups to work with CTSI to improve the health of the San Francisco Bay Area community through a series of health improvement projects directed at high impact conditions; b) create a model system to accelerate the pace of clinical and translational research that includes streamlining regulation, developing participant recruitment services, providing research management, and bringing research services directly into community practices; and, c) improve the performance, transparency and accountability of research administration within and jeyond CTSI by setting challenging goals and tracking performance metrics on public dashboards. These aims will be achieved by orchestration of activities occurring within and between our 10 programs, supported by a proven governance model, and with strong ties to institutional and community leadership. Our ultimate goal is to bring better health to more people more quickly.