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Data Management and Coordinating Center (DMCC)

数据管理和协调中心（DMCC）

基本信息

批准号：
8545224
负责人：
JEFFREY P KRISCHER
金额：
$ 402.41万
依托单位：
UNIVERSITY OF SOUTH FLORIDA
依托单位国家：
美国
项目类别：
财政年份：
2003
资助国家：
美国
起止时间：
2003-09-30 至 2014-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8545224
关键词：
Access to Information Accountability Address Adherence Administrator Adverse event Agreement Algorithms Architecture Archives Area Automatic Data Processing Beds Biological Biological Markers Biological Neural Networks Bite Businesses Cancer Patient Case Report Form Cellular Phone Characteristics Classification Clinic Visits Clinical Clinical Data Clinical Investigator Clinical Management Clinical Protocols Clinical Research Clinical Research Associate Clinical Research Protocols Clinical Trials Clinical Trials Cooperative Group Clinical Trials Data Monitoring Committees Code Collaborations Collection Committee Members Common Data Element Common Terminology Criteria for Adverse Events Communication Communities Computer Architectures Computer Security Computer software Computers Confidentiality Consent Forms Cost Savings Custom Cystic Fibrosis Data Data Analyses Data Base Management Data Collection Data Element Data Protection Data Quality Data Reporting Data Security Data Set Databases Decision Trees Descriptor Development Diagnosis Diagnostic radiologic examination Directories Disasters Disease Documentation Drops Drug Monitoring Electronic Mail Electronics Eligibility Determination Engineering Enrollment Ensure Environment Epidemiology Etiology Evaluation Event Exclusion Criteria Expert Systems Extensible Markup Language Faculty Family Feedback Flare Foundations Freezing Frequencies Funding Future General Population Generations Generic Drugs Genetic Genetic Transcription Genus - Lotus Grant Graph Grouping Growth Guidelines Hand Health Human Resources Image Individual Industry Informatics Information Networks Information Systems Informed Consent Institution Institutional Review Boards Insulin-Dependent Diabetes Mellitus International Internet Interview Label Laboratories Laboratory Research Language Laws Lead Learning Letters Libraries Life Link Location Logic Machine Learning Magnetic Resonance Imaging Mails Malignant Neoplasms Manuals Maps Measures Mechanics Medical Medical History Methodology Methods Metric Modeling Monitor Monitoring Clinical Trials Nature Neurofibromatoses Notification Online Systems Optics Outcome Study Pamphlets Paralysed Participant Pathologic Pathology Patient Outcomes Assessments Patient Self-Report Patients Performance Persons Pharmacy facility Phase Physical environment Physicians Pilot Projects Policies Population Population Study Positron-Emission Tomography Prevention strategy Principal Investigator Printing Privacy Procedures Process Production Programming Languages Proteomics Protocol Compliance Protocols documentation Publications Published Directory Publishing Qualifying Quality Control Quality of life Radiology Specialty Randomized Rare Diseases Reader Recording of previous events Records Recovery Recruitment Activity Registries Regulation Relative (related person)Reporting Research Research Design Research Infrastructure Research Personnel Research Subjects Resolution Resources Risk Role SNOMED Clinical Terms Sampling Scanning Schedule Scientist Secure Security Selection Bias Self Assessment Services Side Single-Gene Defect Site Site Visit Source Specific qualifier value Specimen Stream Structure Support Groups Support System System Techniques Technology Test Result Testing Text Time Training Translations Trees U-Series Cooperative Agreements United States National Institutes of Health Update Validation Variant Videoconferences Videoconferencing Visit Visual Voice Work X-Ray Computed Tomography base clinical research site cluster computing computer science computerized data processing data acquisition data management data mining data modeling data sharing database design database structure demographics design distributed data electronic data eligible participant experience federal policy federated computing firewall follow-up forest graphical user interface improved information display interest meetings member new technology novel strategies operation optical character recognition patient advocacy group patient registry predictive modeling professor programs prospective protocol development quality assurance radiologist remediation repository research study response sample collection software development statistics success symposium technology development therapeutic development tool trafficking user-friendly vector volunteer web interface web page web services web site working group

项目摘要

This application seeks funding for the Data Management and Coordinating Center (DMCC) (formerly known as Data Technology Coordinating Center, DTCC) for the Rare Diseases Clinical Research Network (RDCRN). The applicant, Dr. Krischer, has served as the Principal Investigator for the DTCC for the last 5 years and seeks to renew the cooperative agreement for the DMCC which supports the Rare Diseases Clinical Research Network (RDCRN). The DMCC propose to extend the systems, processes, and procedures developed successfully over the last grant cycle to accommodate the 3000 subjects enrolled on 32 current studies, contingent upon the successful re-competition of their associated clinical research consortia, addition of new studies reflecting the growth of the network, accommodation of federated databases, work with consortia that have pre-existing infrastructure (registries, patient databases, etc.) and registries, provide a user friendly website for web-based recruitment which receives over 3.4 million hits per year at present and a 4000+ member contact registry enhanced for subjects seeking enrollment on clinical trials. We will continue development of new technologies to support scalability and generalizability and tools for cross-disease data mining. Our international clinical information network is secure providing coordinated data management services for collection, storage and analysis of diverse data types from multiple diseases and geographically disparate locations and a portal for the general public and larger community of clinical investigators.

该申请旨在为数据管理和协调中心（DMCC）（以前称为作为数据技术协调中心，DTCC）为罕见疾病临床研究网络（RDCRN）.申请人Krischer博士在过去5年中担任DTCC的主要研究者年，并寻求续签DMCC的合作协议，该协议支持罕见疾病临床研究网络（RDCRN）。DMCC建议扩展系统、流程和在上一个资助周期成功开发了程序，以容纳3000名受试者， 32项当前研究，取决于其相关临床研究的成功再竞争联盟，增加反映网络增长的新研究，数据库，与具有预先存在的基础设施（登记、患者数据库等）的联盟合作和登记处，为网上招聘提供方便的网站，目前已有4000多名成员联系登记，为寻求入组临床研究的受试者增强了联系登记审判我们将继续开发新技术，以支持可伸缩性和通用性以及工具进行跨疾病数据挖掘。我们的国际临床信息网络是安全的，数据管理服务，用于收集、存储和分析多种疾病的不同数据类型和地理上不同的位置，并为公众和更大的临床社区提供门户网站。 investigators.