Eye and Vision Genomics Training Program

描述（由申请人提供）：为了响应RFA-EY-10-001，我们提交了一份经修订的申请，申请人是美国国家眼科研究所（NEI）的Ruth L。Kirschstein国家研究服务奖（NRSA）机构研究补助金（T32），用于开发统计遗传学和基因组信息学方面的新培训计划，重点关注眼部疾病和视力障碍。这个新的培训计划的使命将是培养博士前学生和博士后研究员，使他们成为善于将统计遗传学和生物信息学工具应用于眼部疾病和视力障碍的研究领导者。该提案汇集了来自约翰霍普金斯大学彭博公共卫生学院（SPH）和医学院（SOM）不同部门的统计遗传学，遗传流行病学，生物统计学，眼科学，分子生物学和生物信息学专业知识的教师。我们将从本系招收博士预科生。流行病学（主要是集中在遗传流行病学领域的学生）和系。此外，还将邀请生物统计学博士和对基因组研究的定量方面感兴趣的符合条件的博士后研究员参加SOM（包括威尔默眼科研究所和遗传医学研究所）正在进行的与眼部基因组学相关的研究项目。该计划支持的3名博士前和1名博士后学员将接受有针对性的培训计划，包括：统计遗传学、遗传流行病学、生物统计学和基因组信息学的教学课程。除了项目主任和联合项目主任，11个核心教师沿着与附属学院在视觉研究和遗传学和信息学将有助于这一计划，代表统计遗传学，遗传流行病学，计算统计学，生物统计学，分子遗传学，临床遗传学和眼科学领域。新培训计划的修订申请旨在为学员提供多学科背景，以便在专注于眼部疾病和视觉障碍的基因组研究中进行定量研究。

DESCRIPTION (provided by applicant): In response to RFA-EY-10-001, we are submitting a revised application for a National Eye Institute (NEI) Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Grant (T32) to develop a new training program in statistical genetics and genome informatics focused on eye diseases and vision disorders. The mission of this new training program will be to train pre-doctoral students and post-doctoral fellows to become research leaders adept in applying the tools of statistical genetics and bioinformatics to ocular diseases and vision disorders. This proposal brings together faculty with expertise in statistical genetics, genetic epidemiology, biostatistics, ophthalmology, molecular biology and bioinformatics from different departments in the Johns Hopkins University Bloomberg School of Public Health (SPH) and the School of Medicine (SOM). We will recruit pre-doctoral students from the Dept. of Epidemiology (primarily students in the Genetic Epidemiology Area of Concentration) and the Dept. of Biostatistics, as well as eligible post-doctoral fellows interested quantitative aspects of genomic research and will involve all trainees in ongoing research projects related to ocular genomics in the SOM (including the Wilmer Eye Institute and the Institute of Genetic Medicine). The 3 pre-doctoral and 1 post-doctoral trainees supported by this program will pursue a focused training program consisting of: didactic courses in statistical genetics, genetic epidemiology, biostatistics and genomic informatics. In addition t the Program Director and co-Program Director, 11 Core Faculty along with Affiliate Faculty in vision research and genetics and informatics will contribute to this program, representing the fields of statistical genetics, genetic epidemiology, computational statistics, biostatistics, molecular genetics, clinical genetics and ophthalmology. This revised application for new training program is designed to provide trainees with the multidisciplinary background essential to conduct quantitative studies in genomic research focused on ocular diseases and visual disorders.