Eye and Vision Genomics Training Program

描述(由申请人提供)：为响应RFA-EY-10-001，我们提交了一份修订后的申请，申请国家眼科研究所(NEI)Ruth L.Kirschstein国家研究服务奖(NRSA)机构研究补助金(T32)，以开发专注于眼病和视力障碍的统计遗传学和基因组信息学方面的新培训计划。这一新培训计划的使命将是培养博士后学生和博士后研究员，使他们成为擅长将统计遗传学和生物信息学工具应用于眼部疾病和视力障碍的研究领导者。这项建议汇集了约翰霍普金斯大学彭博公共卫生学院(SPH)和医学院(SOM)不同系的具有统计遗传学、遗传流行病学、生物统计学、眼科学、分子生物学和生物信息学专业知识的教员。我们将从该系招收博士后研究生。流行病学系(主要是遗传流行病学专业的学生)和系。生物统计学研究所以及符合条件的博士后研究员对基因组研究的量化方面感兴趣，并将让所有受训人员参与与眼部基因组学有关的正在进行的研究项目(包括威尔默眼科研究所和遗传医学研究所)。该计划支持的3名博士后和1名博士后实习生将继续进行重点培训计划，包括：统计遗传学、遗传流行病学、生物统计学和基因组信息学的授课课程。除了项目主任和联合项目主任外，11个核心学院以及视觉研究、遗传学和信息学附属学院将为该项目做出贡献，代表统计遗传学、遗传流行病学、计算统计学、生物统计学、分子遗传学、临床遗传学和眼科学等领域。这项修订后的新培训计划申请旨在为受训者提供多学科背景，以进行专注于眼部疾病和视力障碍的基因组研究中的定量研究。

DESCRIPTION (provided by applicant): In response to RFA-EY-10-001, we are submitting a revised application for a National Eye Institute (NEI) Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Grant (T32) to develop a new training program in statistical genetics and genome informatics focused on eye diseases and vision disorders. The mission of this new training program will be to train pre-doctoral students and post-doctoral fellows to become research leaders adept in applying the tools of statistical genetics and bioinformatics to ocular diseases and vision disorders. This proposal brings together faculty with expertise in statistical genetics, genetic epidemiology, biostatistics, ophthalmology, molecular biology and bioinformatics from different departments in the Johns Hopkins University Bloomberg School of Public Health (SPH) and the School of Medicine (SOM). We will recruit pre-doctoral students from the Dept. of Epidemiology (primarily students in the Genetic Epidemiology Area of Concentration) and the Dept. of Biostatistics, as well as eligible post-doctoral fellows interested quantitative aspects of genomic research and will involve all trainees in ongoing research projects related to ocular genomics in the SOM (including the Wilmer Eye Institute and the Institute of Genetic Medicine). The 3 pre-doctoral and 1 post-doctoral trainees supported by this program will pursue a focused training program consisting of: didactic courses in statistical genetics, genetic epidemiology, biostatistics and genomic informatics. In addition t the Program Director and co-Program Director, 11 Core Faculty along with Affiliate Faculty in vision research and genetics and informatics will contribute to this program, representing the fields of statistical genetics, genetic epidemiology, computational statistics, biostatistics, molecular genetics, clinical genetics and ophthalmology. This revised application for new training program is designed to provide trainees with the multidisciplinary background essential to conduct quantitative studies in genomic research focused on ocular diseases and visual disorders.