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The overall objective is to develop Eldecalcitol (ED-71) for colorectal cancer prevention in a preclinical model. Specifically, the Contractor shall obtain required quantities of ED-71, establish the optimal dose and/or non-calcemic dose, perform in depth assessment of ED-7-mediated colon cancer prevention in APC-min mice, in addition to, identifying ED-71 specific molecular target(s) in preventing tumor frequency, incidence, multiplicity, etc. in APC-min mice.
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Patterns of Care/Quality of Care Study - Diagnosis Year 2012; HHSN261201300010I T
  • 批准号:
    8752581
  • 项目类别:
  • 资助金额:
    $2.23万
  • 财政年份:
    2013
  • 负责人:
    Michael Pawlita
  • 依托单位:
Surveillance, Epidemiology, and End Results (SEER) Program
  • 批准号:
    8743667
  • 项目类别:
  • 资助金额:
    $255.05万
  • 财政年份:
    2013
  • 负责人:
    Michael Pawlita
  • 依托单位:
MUC1 Vaccine in Patients with Newly Diagnosed Advanced Adenomas
  • 批准号:
    8762914
  • 项目类别:
  • 资助金额:
    $93.95万
  • 财政年份:
    2013
  • 负责人:
    Michael Pawlita
  • 依托单位:
Core Infrastructure Support
  • 批准号:
    8762909
  • 项目类别:
  • 资助金额:
    $61.21万
  • 财政年份:
    2013
  • 负责人:
    Michael Pawlita
  • 依托单位:
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