Opioid Use Disorder Treatment Linkage at STD Clinics using Buprenorphine (OUTLAST-B)
在 STD 诊所使用丁丙诺啡治疗阿片类药物使用障碍治疗联动 (OUTLAST-B)
基本信息
- 批准号:10348119
- 负责人:
- 金额:$ 68.8万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-04-15 至 2025-01-31
- 项目状态:未结题
- 来源:
- 关键词:Accident and Emergency departmentAdherenceAdmission activityAntibioticsAppointmentAuthorization documentationBehaviorBiological MarkersBuprenorphineCaringCenters for Disease Control and Prevention (U.S.)ClinicClinic VisitsCommunitiesCoupledDataDrug usageEpidemicEventExposure toFentanylFundingHIVHIV InfectionsHealthHealth ServicesHeroinHigh PrevalenceHospitalsHotlinesIndividualIntakeInterviewJailLeadLinkMedicalMethodsMorbidity - disease rateNaloxoneNational Institute of Drug AbuseNurse PractitionersOpiate AddictionOpioid AnalgesicsOutcomeOutpatientsOverdoseParticipantPatientsPharmaceutical PreparationsPhysician AssistantsPhysiciansPopulationPrimary CareProviderPublic HealthRecommendationRegimenReportingResearchResearch DesignResourcesRiskRisk BehaviorsServicesSexually Transmitted DiseasesStatutes and LawsStructureSubstance Use DisorderTestingTimeUnited StatesWalkingWritingarmauthoritybuprenorphine treatmentcare seekingcosteffective therapyeffectiveness evaluationexperiencefollow-uphealth recordhigh riskhigh risk populationillicit opioidinnovationmeetingsmortalitynovelnovel strategiesopioid epidemicopioid useopioid use disorderoverdose deathoverdose preventionpatient navigationpatient navigatorpatient populationprescription opioidprimary outcomepublic health emergencyrandomized, clinical trialstreatment as usualtreatment programtrial comparingusual care armwaiver
项目摘要
Abstract
Untreated opioid use disorder (OUD) is a continuing public health emergency in the United States. OUD is
associated with significant morbidity and mortality, including overdose death. Buprenorphine is an effective
treatment for OUD, but most individuals who need such treatment do not access it.
Public STD clinics are high-volume, episodic care medical settings that serve a high-risk population, often on a
walk-in basis. STD clinic patients have high prevalence of OUD and health-risking behaviors.
This proposed study, entitled Opioid Use Disorder Treatment Linkage at STD Clinics using Buprenorphine
(OUTLAST-B), will examine OUD treatment linkage strategies for opioid-dependent patients seeking services
at public STD clinics. This three-arm, parallel randomized clinical trial (RCT) will compare Usual Care (UC), vs.
referral via Patient Navigation (PN), vs. Patient Navigation with STD-clinic initiated buprenorphine (PN+BUP).
The UC Arm will include standard services at the STD clinic. The PN Arm will include all UC Arm services,
with the addition of a Patient Navigator who will assist the participant in selecting a community OUD treatment
program, facilitate an intake appointment, help to resolve barriers and coordinate OUD treatment entry, and
support early retention in OUD treatment. The PN+BUP Arm will include all PN Arm services, with the addition
of meeting with the STD clinic’s buprenorphine-waivered provider (typically a nurse practitioner) to initiate
buprenorphine treatment, as a bridge until successful transfer to OUD treatment in the community.
Research assessments consisting of a structured interview battery and biomarkers for drug use and STDs will
be conducted at baseline, 3-, and 6-month follow-up. Selected outcomes will be examined through 12-months
via health record linkage methods. The study will examine participant outcomes in the domains of: (1) OUD
treatment entry and retention, (2) Opioid use and related problems (including fatal and non-fatal overdose),
and (3) HIV/STD-related outcomes.
This innovative study could identify new approaches to engaging a high-risk patient population in OUD
treatment. The study could have high impact because findings could be scaled to STD clinics throughout the
nation, spurring novel integration across two traditionally separate service sectors of STD care and OUD
treatment.
摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Jan Gryczynski其他文献
Jan Gryczynski的其他文献
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10705259 - 财政年份:2022
- 资助金额:
$ 68.8万 - 项目类别:
Opioid Use Disorder Treatment Linkage at STD Clinics using Buprenorphine (OUTLAST-B)
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9905496 - 财政年份:2019
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