Influence of superoxide on the central cardiovascular response to emotional stress: cellular and subcellular mechanisms

超氧化物对中枢心血管对情绪应激反应的影响：细胞和亚细胞机制

• 批准号: nhmrc : 472652
• 负责人: Dr Dmitry Mayorov
• 金额: $ 42.85万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/influence-superoxide-central-subcellular-mechanisms/78306
• 关键词: Influence; superoxide; central; cardiovascular; response

Cardiovascular disease is Australia's greatest health problem. It kills more people than any other disease and affected 3.5 million Australians in 2004-05. More and more evidence suggests a relationship between the risk of cardiovascular disease and mental stress. But more research is needed on how stress contributes to heart disease risk. This project aims to determine the role of harmful molecules, called free oxygen radicals, in brain in mediating effects of stress on cardiovascular system.

心血管疾病是澳大利亚最大的健康问题。它比任何其他疾病导致的死亡人数都多，在2004-05年间影响了350万澳大利亚人。越来越多的证据表明，患心血管疾病的风险与精神压力之间存在联系。但关于压力如何导致心脏病风险，还需要更多的研究。该项目旨在确定大脑中被称为氧自由基的有害分子在压力对心血管系统的影响中的作用。