2013 Stochastic Physics in Biology GRC

2013 生物随机物理 GRC

• 批准号: 8454775
• 负责人: HONG QIAN
• 金额: $ 1.86万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-12-14 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8454775
• 关键词: Address; Affect; Age; Area; Behavior; Biochemical; Biological; Biology; Biomedical Research; Biophysics; California; Cancer Immunology Science; Cell Differentiation process; Cell physiology; Cells; Cellular biology; Chemistry; Collection; Complex; Computers; DNA-Protein Interaction; Data; Development; Dill; Discipline; Engineering; Environment; Epigenetic Process; Equilibrium; Evolution; Facial Expression; Feedback; Foundations; Gene Expression; Gene Expression Regulation; Genome; Goals; Health; Heterogeneity; Individuality; International; Investigation; Laboratories; Lead; Life; Light; Malignant Neoplasms; Mathematics; Measurement; Measures; Medicine; Metabolism; Methods; Minor; Molecular; Noise; Oncogenes; Outcome; Physics; Population; Problem Solving; Process; Proteins; Request for Proposals; Research; Research Personnel; Resolution; Role; Running; Science; Scientist; Signaling Molecule; Stem Cell Research; System; Systems Biology; Time; Tissues; United States National Institutes of Health; Variant; Writing; biological systems; carcinogenesis; improved; meetings; next generation; public health relevance; research study; single molecule; symposium; tool; transcription factor; trend

DESCRIPTION (provided by applicant): This proposal requests partial support for an international, interdisciplinary conference on Stochastic Physics in Biology GRC. This is the 2nd installment of a new Gordon Research Conference, which will be held January 13 - 18, 2013 in Ventura, California. The broad long-term goal is to bring experimental biologists together with physical scientists, engineers and applied mathematicians to better understand the cellular behavior, function and evolution in terms of a new, stochastic dynamic description, provide a conduit between molecular cellular and evolutionary biology. The specific aim of this second meeting is to introduce the foundations for stochastic dynamical descriptions of living processes, and to discuss the trend of current biomedical research, which reveals cellular molecular fluctuations, nonlinear feedbacks, and emergent behaviors at different time scales. There will be 27 speakers and 9 session chairs. Some are leading molecular biologists with significant contributions, other are active young researchers at the leading edge. The meeting will bring together this diverse group of scientists to help establish this emerging new discipline. Researchers will discuss fundamental questions, approaches, and principles relating to how cells function, develop and evolve in the presence of noise and fluctuations at the mesoscopic scale. The significance of this application is in developing a new stochastic dynamical description of cellular processes through this new meeting that will provide a long-running venue to bring together researchers from physical and biological disciplines. Thus, this meeting will help support two new NIH initiatives, recently announced, that aim to "bridge the sciences", by bringing physical scientists together with biological scientists to solve problems of biomedical importance. The health relatedness of the application is in better understanding fundamental biology and in helping to realize the potential of systems biology in biomedicine.

描述（由申请人提供）：该提案要求对生物学GRC中的随机物理学国际跨学科会议提供部分支持。这是一个新的戈登研究会议，将于2013年1月13日至18日在文图拉，加州的第二部分。广泛的长期目标是将实验生物学家与物理科学家，工程师和应用数学家聚集在一起，以更好地理解细胞行为，功能和进化，以一种新的随机动态描述，提供分子细胞和进化生物学之间的管道。第二次会议的具体目的是介绍生命过程的随机动力学描述的基础，并讨论当前生物医学研究的趋势，揭示细胞分子波动，非线性反馈和不同时间尺度的涌现行为。将有27名发言人和9名会议主席。一些是具有重大贡献的领先分子生物学家，另一些是活跃在前沿的年轻研究人员。这次会议将汇集这一不同的科学家群体，以帮助建立这一新兴的新学科。研究人员将讨论有关细胞如何在介观尺度的噪声和波动存在下发挥作用，发展和进化的基本问题，方法和原则。这项应用的意义在于通过这次新的会议开发一种新的细胞过程的随机动力学描述，这将提供一个长期运行的场所，将物理和生物学科的研究人员聚集在一起。因此，这次会议将有助于支持国家卫生研究院最近宣布的两项新的倡议，其目的是通过将物理科学家与生物科学家聚集在一起，解决具有生物医学重要性的问题，从而“架起科学的桥梁”。该应用程序的健康相关性是更好地理解基础生物学，并帮助实现系统生物学在生物医学中的潜力。