Inhibiting the oncogenic cross-talk between cancer cells and surrounding stroma by targeting the metastasis suppressor NDRG1 in pancreatic cancer
Inhibiting the oncogenic cross-talk between cancer cells and surrounding stroma by targeting the metastasis suppressor NDRG1 in pancreatic cancer
通过靶向胰腺癌转移抑制因子 NDRG1 抑制癌细胞与周围基质之间的致癌串扰
批准号：
nhmrc : GNT1160968
负责人：
金额：
$19.97万
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2019
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2019-01-01 至 --
中文摘要
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英文摘要
The stromal tissue surrounding pancreatic cancer is a major driver of metastasis and therapeutic resistance. This proposal will examine a breakthrough drug in clinical trials that up-regulates the potent metastasis suppressor, NDRG1, and its role in inhibiting the oncogenic cross-talk between pancreatic cancer cells and the surrounding stroma.
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