ACS-TR19 CYCLOTRON

ACS-TR19 回旋加速器

• 批准号: 8334887
• 负责人: ROBERT C MCKINSTRY
• 金额: $ 200万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-08-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8334887
• 关键词: Clinical; Cyclotrons; Funding; Growth; Image; Inpatients; Isotopes; Location; Maintenance; Outpatients; Positron; Positron-Emission Tomography; Production; Radioisotopes; Radiology Specialty; Radiopharmaceuticals; Request for Applications; Research; Research Project Grants; System; United States National Institutes of Health; Universities; Washington; flexibility; improved; particle; research study

DESCRIPTION (provided by applicant): This revised application requests funds to purchase a TR19 dual particle cyclotron manufactured by Advance Cyclotron Systems which is necessary to support ongoing and future research growth at Washington University. The combination of features within the TR19 is optimal for supporting the diverse number of PET radionuclides and radiopharmaceuticals needed to support our NIH-funded research. The TR19 which is the only machine suitable to produce a broad spectrum of positron-emitting isotopes including Cu-64, Zr-89, I-124; it is also ideal for increasing the production of "standard" radionuclides such as C-11, F-18, an O-15 required for our clinical imaging studies. The TR19 will be installed in the Department of Radiology at Washington University (WU). WU has ongoing inpatient and outpatient research near this location that offers unique clinical and collaborative research projects. The TR19 will fulfill the long-term objective to increase our ability to support ongoing and future research growth at Washington University by providing a more reliable and flexible platform that will double the radioisotope production capacity of our cyclotron facility. By significantly enhancing our reliability to produce radioisotopes, PET research can continue without concern of complications due to frequent and severe maintenance issues leading to unavoidable downtown and the cancellation of research studies. Unlike the current CS-15 and JSW168 cyclotrons, the TR19 will allow increased efficiency and flexibility for non-standard isotope production as well as improved production capabilities of the standard PET radionuclides.

描述（由申请人提供）：此修订后的申请要求资金购买先进回旋加速器系统制造的TR 19双粒子回旋加速器，这是必要的，以支持正在进行和未来的研究增长在华盛顿大学。TR 19内的功能组合对于支持我们NIH资助的研究所需的各种PET放射性核素和放射性药物是最佳的。TR 19是唯一适合生产广谱正电子发射同位素（包括Cu-64、Zr-89、I-124）的机器;它也是增加“标准”放射性核素（例如C-11、I-124）产量的理想选择。 F-18，O-15我们的临床成像研究需要。TR 19将安装在华盛顿大学（WU）放射科。WU在这个位置附近正在进行住院和门诊研究，提供独特的临床和合作研究项目。TR 19将实现长期目标，通过提供一个更可靠和灵活的平台，将我们的回旋加速器设施的放射性同位素生产能力增加一倍，提高我们支持华盛顿大学正在进行和未来研究增长的能力。通过显著提高我们生产放射性同位素的可靠性，PET研究可以继续进行，而不必担心由于频繁和严重的维护问题导致的并发症，这些问题导致不可避免的市中心和研究的取消。与目前的CS-15和JSW 168回旋加速器不同，TR 19将提高非标准同位素生产的效率和灵活性，并提高标准PET放射性核素的生产能力。