Developmental Research Program

该发展研究计划（DRP）将通过资助莫菲特研究人员提出的试点项目，促进对转化性皮肤恶性肿瘤研究的创新理念的探索；它将不支持现有完整项目的扩展。弗农·桑达克博士将领导DRP。他一直是NCI小组委员会G（培训补助金）的成员，是佛罗里达州颁发的第一个Pre-SPORE补助金的首席研究员。他指导了数十名外科肿瘤学家，被称为杰出的导师。为了最大限度地提高资助项目在必要时能够作为替代项目的可能性，DRP将支持建立新的合作关系，并促进其他相关领域的有才华的研究者（即皮肤肿瘤学的新研究者）参与皮肤恶性肿瘤研究，或促进已经在皮肤恶性肿瘤领域建立的研究者进行有前途的早期研究。DRP的一个创新之处在于，研究人员将被鼓励提出一些项目，这些项目虽然位于莫菲特，但可能涉及与另一个皮肤孢子机构的已建立的皮肤孢子项目合作，或者与现有的莫菲特肺孢子合作。与莫菲特肺孢子合作，每年最多一个DRP奖将由皮肤孢子作为交叉孢子互动共同支持。鼓励与正在进行的Moffitt Skin SPORE项目相关联的DRP项目。DRP每年将为至多三个试点项目提供指导、建议、评估和资金。每个试点项目的目标是在皮肤恶性肿瘤预防、治疗、基础研究或应用研究领域产生足够的高质量数据，以便向NIH或其他联邦机构提交独立项目以获得同行评审资金。此外，如果现有的完整项目完成或未能达到由Skin SPORE外部咨询委员会（EAB）与该Skin SPORE领导层确定的转化目标和期望，开发项目可以作为潜在的替代项目提升到完整项目状态。由奖励评估委员会（AEC）资助的DRP项目的选择将模仿NIH研究部门的审查过程。AEC将由弗农·桑达克博士主持。每个试点项目将有三个审稿人，一个主要审稿人，一个次要审稿人和一个统计审稿人。三位审稿人将被要求使用NIH评分系统为项目分配1.0到9.0的优先级分数。研究人员对皮肤肿瘤学的新项目将给予高度重视。

This Developmental Research Program (DRP) will promote the exploration of innovative ideas in translational cutaneous malignancy research through the funding of pilot projects proposed by Moffitt investigators; it will not support extensions of existing full projects. Dr. Vernon Sondak will lead the DRP. He has been a member of NCI Subcommittee G (training grants) and was the Principal Investigator of the first Pre-SPORE grant awarded by the State of Florida. He has mentored dozens of surgical oncologists and is known as an outstanding mentor. To maximize the likelihood that funded projects will be able to serve as replacement projects if needed, the DRP will support the establishment of new collaborations as well as facilitate either a talented investigator in another relevant field, i.e. a new investigator to cutaneous oncology, to become involved in cutaneous malignancy research or promote promising early research by an investigator already established in the cutaneous malignancy field. An innovative feature of the DRP is that investigators will be encouraged to propose projects that, while based at Moffitt, might involve a collaboration with an established Skin SPORE project at another Skin SPORE institution, or with the existing Moffitt Lung SPORE. In collaboration with the Moffitt Lung SPORE, up to one DRP award per year will be co-supported by the Skin SPORE as a cross-SPORE interaction. DRP projects that link to an ongoing Moffitt Skin SPORE project are encouraged. The DRP will provide guidance, advice, evaluation, and funding for up to three pilot projects per year. The goal for each pilot project is to generate sufficient high-quality data in the field of cutaneous malignancy prevention, treatment, basic research, or applied research to allow for submission of an independent project to the NIH or other federal agency for peer review funding. In addition, developmental projects could serve as potential replacement projects elevated to full project status if an existing full project is completed or fails to meet its translational goals and expectations as determined by the Skin SPORE External Advisory Board (EAB) in conjunction with the leadership of this Skin SPORE. The selection of DRP projects for funding by the Award Evaluation Committee (AEC) will be modeled after the NIH study section review process. The AEC will be chaired Dr. Vernon Sondak. Each pilot project will have three reviewers, a primary reviewer, a secondary reviewer, and a statistical reviewer. The three reviewers will be asked to assign priority scores from 1.0 to 9.0 to the project using the NIH scoring system. Projects from investigators new to cutaneous oncology will be given a high priority.