Developmental Research Program

这一发展研究计划(DRP)将通过资助莫菲特研究人员提出的试点项目来促进对转化性皮肤恶性肿瘤研究的创新想法的探索；它不会支持现有完整项目的扩展。弗农·桑达克博士将领导DRP。他一直是NCI小组委员会G(培训补助金)的成员，并是佛罗里达州授予的第一个孢子前补助金的首席调查员。他曾指导过数十位外科肿瘤学家，被认为是一位杰出的导师。为了最大限度地提高资助项目在需要时作为替代项目的可能性，DRP将支持建立新的合作关系，并促进另一个相关领域的有才华的研究员，即皮肤肿瘤学的新研究员，参与皮肤恶性肿瘤研究，或促进已在皮肤恶性肿瘤领域建立的研究员进行有前途的早期研究。DRP的一个创新特点是，将鼓励研究人员提出项目，这些项目虽然设在莫菲特，但可能涉及与另一家皮肤孢子机构的现有皮肤孢子项目合作，或与现有的莫菲特肺孢子合作。在与莫菲特肺孢子的合作下，皮肤孢子将作为一种交叉孢子相互作用，每年最多支持一个DRP奖。DRP项目，链接到正在进行的莫菲特皮肤孢子项目是鼓励的。DRP每年将为最多三个试点项目提供指导、建议、评估和资金。每个试点项目的目标是在皮肤恶性肿瘤的预防、治疗、基础研究或应用研究领域产生足够的高质量数据，以便向NIH或其他联邦机构提交独立的项目，以获得同行审查资金。此外，如果现有的完整项目完成或未能达到皮肤孢子外部咨询委员会(EAB)与该皮肤孢子的领导层共同确定的翻译目标和期望，发展项目可以作为潜在的替代项目，提升到完全项目状态。由奖项评估委员会(AEC)选择DRP项目的资助将仿效NIH研究部分的审查过程。AEC将由Vernon Sondak博士担任主席。每个试点项目将有三名审查员，一名主要审查员、一名二级审查员和一名统计审查员。三位评审员将被要求使用NIH评分系统为该项目分配从1.0到9.0的优先分数。从新的研究人员到皮肤肿瘤学的项目将得到高度优先考虑。

This Developmental Research Program (DRP) will promote the exploration of innovative ideas in translational cutaneous malignancy research through the funding of pilot projects proposed by Moffitt investigators; it will not support extensions of existing full projects. Dr. Vernon Sondak will lead the DRP. He has been a member of NCI Subcommittee G (training grants) and was the Principal Investigator of the first Pre-SPORE grant awarded by the State of Florida. He has mentored dozens of surgical oncologists and is known as an outstanding mentor. To maximize the likelihood that funded projects will be able to serve as replacement projects if needed, the DRP will support the establishment of new collaborations as well as facilitate either a talented investigator in another relevant field, i.e. a new investigator to cutaneous oncology, to become involved in cutaneous malignancy research or promote promising early research by an investigator already established in the cutaneous malignancy field. An innovative feature of the DRP is that investigators will be encouraged to propose projects that, while based at Moffitt, might involve a collaboration with an established Skin SPORE project at another Skin SPORE institution, or with the existing Moffitt Lung SPORE. In collaboration with the Moffitt Lung SPORE, up to one DRP award per year will be co-supported by the Skin SPORE as a cross-SPORE interaction. DRP projects that link to an ongoing Moffitt Skin SPORE project are encouraged. The DRP will provide guidance, advice, evaluation, and funding for up to three pilot projects per year. The goal for each pilot project is to generate sufficient high-quality data in the field of cutaneous malignancy prevention, treatment, basic research, or applied research to allow for submission of an independent project to the NIH or other federal agency for peer review funding. In addition, developmental projects could serve as potential replacement projects elevated to full project status if an existing full project is completed or fails to meet its translational goals and expectations as determined by the Skin SPORE External Advisory Board (EAB) in conjunction with the leadership of this Skin SPORE. The selection of DRP projects for funding by the Award Evaluation Committee (AEC) will be modeled after the NIH study section review process. The AEC will be chaired Dr. Vernon Sondak. Each pilot project will have three reviewers, a primary reviewer, a secondary reviewer, and a statistical reviewer. The three reviewers will be asked to assign priority scores from 1.0 to 9.0 to the project using the NIH scoring system. Projects from investigators new to cutaneous oncology will be given a high priority.