Developmental Research Program

发展研究计划

• 批准号: 8556458
• 负责人: VERNON K. SONDAK
• 金额: $ 5.64万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-20 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8556458
• 关键词: Applied Research; Award; Basic Science; Collaborations; Cutaneous; Development; Evaluation; Florida; Funding; Goals; Grant; Institution; Lead; Leadership; Link; Lung; Malignant Neoplasms; Mentors; Modeling; Oncology; Peer Review; Pilot Projects; Prevention; Principal Investigator; Process; Program Research Project Grants; Research; Research Personnel; Skin; Skin Cancer; Study Section; Surgical Oncologist; System; Training; United States National Institutes of Health; base; data quality; expectation; innovation; meetings; member; programs; success

This Developmental Research Program (DRP) will promote the exploration of innovative ideas in translational cutaneous malignancy research through the funding of pilot projects proposed by Moffitt investigators; it will not support extensions of existing full projects. Dr. Vernon Sondak will lead the DRP. He has been a member of NCI Subcommittee G (training grants) and was the Principal Investigator of the first Pre-SPORE grant awarded by the State of Florida. He has mentored dozens of surgical oncologists and is known as an outstanding mentor. To maximize the likelihood that funded projects will be able to serve as replacement projects if needed, the DRP will support the establishment of new collaborations as well as facilitate either a talented investigator in another relevant field, i.e. a new investigator to cutaneous oncology, to become involved in cutaneous malignancy research or promote promising early research by an investigator already established in the cutaneous malignancy field. An innovative feature of the DRP is that investigators will be encouraged to propose projects that, while based at Moffitt, might involve a collaboration with an established Skin SPORE project at another Skin SPORE institution, or with the existing Moffitt Lung SPORE. In collaboration with the Moffitt Lung SPORE, up to one DRP award per year will be co-supported by the Skin SPORE as a cross-SPORE interaction. DRP projects that link to an ongoing Moffitt Skin SPORE project are encouraged. The DRP will provide guidance, advice, evaluation, and funding for up to three pilot projects per year. The goal for each pilot project is to generate sufficient high-quality data in the field of cutaneous malignancy prevention, treatment, basic research, or applied research to allow for submission of an independent project to the NIH or other federal agency for peer review funding. In addition, developmental projects could serve as potential replacement projects elevated to full project status if an existing full project is completed or fails to meet its translational goals and expectations as determined by the Skin SPORE External Advisory Board (EAB) in conjunction with the leadership of this Skin SPORE. The selection of DRP projects for funding by the Award Evaluation Committee (AEC) will be modeled after the NIH study section review process. The AEC will be chaired Dr. Vernon Sondak. Each pilot project will have three reviewers, a primary reviewer, a secondary reviewer, and a statistical reviewer. The three reviewers will be asked to assign priority scores from 1.0 to 9.0 to the project using the NIH scoring system. Projects from investigators new to cutaneous oncology will be given a high priority.

该发展研究计划（DRP）将通过资助莫菲特研究人员提出的试点项目，促进转化皮肤恶性肿瘤研究创新理念的探索；它不支持现有完整项目的扩展。 Vernon Sondak 博士将领导 DRP。他曾是 NCI G 小组委员会（培训资助）的成员，并且是佛罗里达州授予的第一笔 Pre-SPORE 资助的首席研究员。他指导过数十位肿瘤外科医师，被誉为杰出导师。为了最大限度地提高受资助项目在需要时能够充当替代项目的可能性，DRP 将支持建立新的合作，并促进另一个相关领域的才华横溢的研究者（即皮肤肿瘤学的新研究者）参与皮肤恶性肿瘤研究，或促进皮肤恶性肿瘤领域已有的研究者进行有前途的早期研究。 DRP 的一个创新特点是，鼓励研究人员提出基于莫菲特的项目，这些项目可能涉及与另一个 Skin SPORE 机构已建立的 Skin SPORE 项目或与现有的 Moffitt Lung SPORE 合作。与 Moffitt Lung SPORE 合作，每年将由 Skin SPORE 共同支持一项 DRP 奖项，作为跨 SPORE 的互动。鼓励与正在进行的 Moffitt Skin SPORE 项目相关的 DRP 项目。 DRP 每年将为最多三个试点项目提供指导、建议、评估和资金。每个试点项目的目标是在皮肤恶性肿瘤预防、治疗、基础研究或应用研究领域生成足够的高质量数据，以便向 NIH 或其他联邦机构提交独立项目以获得同行评审资金。此外，如果现有完整项目已完成或未能达到 Skin SPORE 外部顾问委员会 (EAB) 与 Skin SPORE 领导层共同确定的转化目标和期望，则开发项目可以作为提升为完整项目状态的潜在替代项目。奖励评估委员会 (AEC) 资助的 DRP 项目的选择将效仿 NIH 研究部门的审查流程。 AEC 将由 Vernon Sondak 博士担任主席。每个试点项目将有三名评审员，一名初级评审员、一名二级评审员和一名统计评审员。三位评审员将被要求使用 NIH 评分系统为项目分配从 1.0 到 9.0 的优先级分数。皮肤肿瘤学新手的研究人员的项目将得到高度优先。