Fish oil for HIV- Related Infiamm-aging and Immune Senescence

鱼油治疗 HIV 相关炎症衰老和免疫衰老

• 批准号: 8552038
• 负责人: BARBARA ANN SWANSON
• 金额: $ 7.73万
• 依托单位: RUSH UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-02-01 至 2017-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8552038
• 关键词: AIDS/HIV problem; African American; Age; Age of Onset; Aging; Anti-Inflammatory Agents; Anti-inflammatory; Cardiac; Cardiovascular Diseases; Chronic; Cohort Studies; Comorbidity; Data; Development; Elderly; Fish Oils; HIV; HIV Infections; Health Status; Heart Diseases; Immune; Infection; Inflammation; Instruction; Lead; Life; Link; Malignant Neoplasms; Metabolic syndrome; Minority; Osteoporosis; Persons; Phenotype; Race; Risk; Serum; Testing; United States; age group; cytokine; middle age; premature; senescence

PROJECT SUMMARY (See instructions): HIV infection is associated with the premature onset of age-associated co-morbidities such as non-AIDS malignancies and cardiovascular disease. These co-morbidities have been linked to persistently elevated serum levels of proinflammatory cytokines that mimic an aging phenotype known as

项目摘要（参见说明）： HIV 感染与年龄相关的合并症（例如非艾滋病恶性肿瘤和心血管疾病）的过早发病有关。这些合并症与促炎细胞因子的血清水平持续升高有关，这些细胞因子模仿了一种称为衰老表型的衰老表型。