Eleventh Annual AACR International Conference on Frontiers in Cancer Prevention R

第十一届 AACR 癌症预防前沿国际会议

• 批准号: 8461731
• 负责人: Margaret Foti
• 金额: $ 2.5万
• 依托单位: AMERICAN ASSOCIATION FOR CANCER RESEARCH
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-11 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8461731
• 关键词: Advocate; American Association of Cancer Research; Attention; Awareness; Basic Science; Behavioral; Behavioral Sciences; California; Carcinogens; Clinical; Collaborations; Colonoscopy; Colorectal Cancer; Data; Discipline; Disease; Early Diagnosis; Early treatment; Education; Effectiveness; Epidemiology; Event; Evolution; Exercise; Exposure to; Fertilization; Fostering; General Population; Government; Head; Health Professional; Hepatitis B Virus; Human; Human Papillomavirus; Imaging Techniques; Incidence; Individual; Industry; Information Technology; International; Intervention; Learning; Lesion; Life Style; Mainstreaming; Malignant Neoplasms; Malignant neoplasm of cervix uteri; Malignant neoplasm of lung; Mammography; Molecular; Pap smear; Patients; Physicians; Population; Premalignant; Prevention; Prevention Research; Prevention approach; Prevention strategy; Primary Prevention; Process; Public Health; Recurrence; Research; Research Personnel; Research Technics; Risk; Scientific Advances and Accomplishments; Scientist; Screening procedure; Second Primary Cancers; Secondary Prevention; Series; Shapes; Specific qualifier value; Survivors; Tobacco; Translating; cancer prevention; carcinogenesis; career; clinical application; frontier; interdisciplinary collaboration; interest; lectures; malignant breast neoplasm; mortality; posters; prevent; programs; skills; symposium; tertiary prevention; vaccine development

DESCRIPTION (provided by applicant): The Eleventh Annual International Conference on Frontiers in Cancer Prevention Research will take place October 16-19, 2012, at the Hilton Anaheim Hotel in Anaheim, California. The AACR has long been a supporter of cancer prevention research aimed at preventing cancer through lifestyle changes and early detection and treatment. This annual AACR conference debuted in 2002 and remains the pre-eminent cancer prevention research conference in the world. Physicians, scientists, patients, and survivor advocates learn about the latest translational discoveries from the leading basic, clinical, epidemiologic, and behavioral scientists in the field. The conference fosters interdisciplinary collaborations, accelerates progression in the field of prevention research, and promotes awareness of the vital importance of cancer prevention in reducing cancer incidence and mortality. The theme for this year's conference is "Integrative Cancer Prevention". The program will focus on identifying the factors that contribute to the initiation and evolution of cancer and how our understanding of these factors can be used to identify those at risk, identify approaches for prevention, and assess such approaches in the general population. The conference will not only focus on where the field of cancer prevention research is headed and how it is evolving, but will also help to shape and define the evolution of cancer prevention research. Bringing together basic, clinical, and population approaches in a unified way to study cancer prevention research in the broadest terms will help to promote cross-fertilization of scientists from diverse disciplines. Scientific advances are transforming the field of cancer prevention by providing us with the information and technology needed to understand the molecular underpinnings of carcinogenesis in humans and to identify and intervene in disease processes with unprecedented accuracy and effectiveness. By translating our understanding of the basic science into clinical application, benefits are being seen at the public health level. Several steps within carcinogenic initiation and progression are targets for cancer prevention. Primary prevention is the avoidance of exposure to carcinogens or the carcinogenic process and may be directed at the broad population of individuals who show no sign of pre-malignancy. Exercise and avoidance of tobacco are examples of this type of intervention. And one of the most successful primary prevention strategies is the development of vaccines such as those for HBV and HPV. Secondary prevention efforts are receiving a lot of attention and include screening and early detection, which are generally directed toward a more specified risk population. Examples of this type of prevention include pap test (for cervical cancer), mammography (for breast cancer), colonoscopy (for colorectal cancer) and emerging new imaging techniques to detect breast and lung cancer. Studies have found that premalignant lesions may be more common than previously realized and it will be crucial to understand who some premalignant lesions progress to cancer and others do not. Finally, tertiary prevention is aimed at preventing recurrence or second cancers. PUBLIC HEALTH RELEVANCE: This conference promotes public, academic, government, and industry awareness of the vital importance of cancer prevention research in reducing cancer incidence and mortality. It also catalyzes coordinated, focused research in basic, clinical, epidemiologic and behavioral science that promises to accelerate cancer prevention. Recent scientific advances are providing us with the information and technology needed to elucidate the molecular underpinnings of carcinogenesis in humans; understanding why some premalignant lesions progress to cancer while others do not will be crucial to personalizing therapy and avoiding overtreatment of patients. Through a combination of didactic lectures, poster presentations, educational sessions, and informal networking events, this conference provides a venue for scientists, physicians, and other health professionals to learn about and discuss the most cutting-edge research in the field and form interdisciplinary collaborations that will accelerate progression in cancer prevention research.

第十一届癌症预防研究前沿国际会议将于2012年10月16日至19日在加州阿纳海姆的希尔顿阿纳海姆酒店举行。长期以来，AACR一直是癌症预防研究的支持者，旨在通过改变生活方式和早期发现和治疗来预防癌症。AACR年度会议于2002年首次举办，至今仍是世界上最杰出的癌症预防研究会议。医生、科学家、患者和幸存者倡导者从该领域领先的基础、临床、流行病学和行为科学家那里了解最新的转化发现。会议促进跨学科合作，加速预防研究领域的进展，并促进对癌症预防在降低癌症发病率和死亡率方面至关重要的认识。今年会议的主题是“综合癌症预防”。该项目将侧重于确定导致癌症发生和演变的因素，以及我们对这些因素的理解如何用于识别那些有风险的人，确定预防方法，并在普通人群中评估这些方法。会议不仅将关注癌症预防研究领域的发展方向和发展趋势，还将有助于塑造和定义癌症预防研究的发展。以统一的方式将基础、临床和人口方法结合在一起，以最广泛的方式研究癌症预防研究，将有助于促进来自不同学科的科学家的交叉受精。科学进步正在改变癌症预防领域，为我们提供了了解人类致癌的分子基础所需的信息和技术，并以前所未有的准确性和有效性识别和干预疾病过程。通过将我们对基础科学的理解转化为临床应用，我们在公共卫生层面看到了益处。癌症发生和发展的几个步骤是癌症预防的目标。初级预防是指避免接触致癌物或致癌过程，可针对没有表现出恶性前病变迹象的广大人群。运动和不吸烟就是这类干预的例子。最成功的一级预防策略之一是开发乙肝病毒和人乳头瘤病毒等疫苗。二级预防工作正在受到很多关注，包括筛查和早期发现，这些工作通常针对更具体的风险人群。这类预防的例子包括巴氏涂片检查（用于宫颈癌）、乳房x光检查（用于乳腺癌）、结肠镜检查（用于结肠直肠癌）以及用于检测乳腺癌和肺癌的新成像技术。研究发现，癌前病变可能比以前认识到的更常见，了解哪些癌前病变会发展为癌症，哪些不会，将是至关重要的。最后，三级预防的目的是防止复发或第二次癌症。