2012 Lipoprotein Metabolism Gordon Research Conference and Gordon Research Semina

2012年脂蛋白代谢戈登研究会议暨戈登研究研讨会

• 批准号: 8318336
• 负责人: ROBERT O'Mara RYAN
• 金额: $ 1.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-15 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8318336
• 关键词: ATP-Binding Cassette Transporters; Accounting; Address; African American; American; Animal Model; Apolipoproteins B; Area; Atherosclerosis; Basic Science; Biochemistry; Bioinformatics; Biological; Biological Models; Biology; Cardiovascular Diseases; Cells; Cholesterol; Cholesterol Homeostasis; Clinical; Commit; Consultations; Development; Diagnosis; Disease; Dyslipidemias; Ensure; Event; Family member; Fostering; Gender; Generations; Genetic; Genomics; Goals; Health; Human; Individual; International; Interpersonal Relations; Knowledge; Lipids; Lipolysis; Lipoproteins; Low Density Lipoprotein Receptor; Metabolism; Mission; Molecular; National Heart, Lung, and Blood Institute; Oral; Participant; Pathway interactions; Patients; Pharmaceutical Preparations; Plasma; Postdoctoral Fellow; Prevention; Primary Prevention; Process; Proteomics; Public Health; Qualifying; Regulation; Reporting; Research; Research Personnel; Residual state; Resort; Risk; Role; Schedule; Science; Scientist; Secondary Prevention; Systems Analysis; Technology; Therapeutic; Time; Training; Translating; Translational Research; Translations; Woman; Work; abstracting; cardiovascular risk factor; career development; design; graduate student; high density lipoprotein-3; human disease; human population study; improved; interest; knowledge base; lipid metabolism; lipid transport; meetings; member; metabolomics; novel therapeutic intervention; particle; posters; programs; public health relevance; social; success; symposium; unpublished works

DESCRIPTION (provided by applicant): We request partial support of the 2012 Gordon Research Conference on Lipoprotein Metabolism to be held at Waterville Valley Resort, NH on June 17 - 22 in conjunction with a Gordon Research Seminar (June 16-17). The Chair, Dr. Robert Ryan, in consultation with past chairs, the 2014 vice chairs, and leaders in the field, have planned nine oral sessions: Session 1: The Control of Lipolysis in Plasma Session 2: Regulation of Cholesterol Homeostasis Session 3: High-density lipoprotein: impact of particle diversity Session 4: Apolipoprotein B and TG-rich Lipoprotein Assembly Session 5: Expanding Role of Low Density Lipoprotein Receptor Family Members Session 6: Cholesterol efflux, ABC Transporters and Disease Session 7: Advances in Therapies to Treat Cardiovascular Disease Session 8: Intracellular Lipid Transport and Lipid Droplet Biology Session 9: State of the Art: Genomics, Proteomics and Metabolomics Our conference satisfies all aspects of the NHLBI Mission. First, we bring together international leaders in lipoprotein metabolism, a mechanism that accounts for 30% of global cardiovascular risk burden. Second, gender-related issues of genetics, biology, biochemistry and clinical manifestations of lipoproteins have been identified, so our conference satisfies the NHLBI responsibility for addressing these issues in women. Two Discussion Leaders are women, and an African-American, Dr. Debose-Boyd, will be a major speaker in Session 2. Our conference has been carefully coordinated to include diversity of research related to the causes, prevention, diagnosis and treatment of dyslipidemias and cardiovascular disease. Fourth, the NHLBI has traditionally supported our meeting and we have been honored to invite selected members of NHLBI administration as attendees. Fifth, we share the NHLBI's priority on prevention; indeed key aspects of primary and secondary prevention of cardiovascular disease that are currently in widespread routine clinical use (e.g. statin drugs) were first reported at our past meetings. Sixth, the Chair has placed the highest priority on participation by individuals early in their training and early in their career development. The Gordon Research Seminar component will have four sessions (to be finalized after the review of submitted abstracts) with presentations by young investigators.

描述（由申请人提供）：我们请求部分支持2012年戈登脂蛋白代谢研究会议将于6月17日至22日在沃特维尔山谷度假村，NH与戈登研究研讨会（6月16日至17日）一起举行。主席罗伯特·瑞安博士与过去的主席、2014年副主席和该领域的领导人协商， 计划的九次口头会议：第一部分：控制血浆中的脂肪分解第2节：胆固醇稳态的调节第3节：高密度脂蛋白：颗粒多样性的影响第4节：载脂蛋白B和富含TG的脂蛋白组装第5节：低密度脂蛋白受体家族成员的扩展作用第6节：胆固醇流出、ABC转运蛋白和疾病第7节：治疗心血管疾病的进展第8节：细胞内脂质运输和脂滴生物学会议9：最先进的：基因组学，蛋白质组学和代谢组学我们的会议满足NHLBI使命的各个方面。首先，我们汇集了脂蛋白代谢方面的国际领导者，这一机制占全球心血管风险负担的30%。第二，与性别有关的遗传学，生物学，生物化学和脂蛋白的临床表现的问题已经确定，所以我们的会议满足NHLBI的责任，解决这些问题的妇女。两名讨论领导人是妇女，一名非洲裔美国人Debose-Boyd博士将是第二次会议的主要发言人。我们的会议经过精心协调，包括与血脂异常和心血管疾病的原因，预防，诊断和治疗相关的研究的多样性。第四，NHLBI传统上一直支持我们的会议，我们很荣幸邀请NHLBI行政部门的选定成员参加。第五，我们同意NHLBI对预防的优先考虑;事实上，目前广泛常规临床使用的心血管疾病一级和二级预防的关键方面（例如他汀类药物）首次在我们过去的会议上报告。第六，主席高度重视个人在培训初期和职业发展初期的参与。戈登研究研讨会部分将有四个会议（将在提交的摘要审查后定稿），由年轻的研究人员介绍。