DEVELOPMENTAL RESEARCH PROGRAM

爱荷华大学/马约诊所淋巴瘤孢子（UI/MC孢子）发展的目标 研究计划是为了支持创新，科学合理的项目，调查有关问题 转移性淋巴瘤的研究该计划非常成功，过去和现在的支持超过 在过去的4年里，我们进行了13个发展研究项目。其中三个项目已收到 外部，同行评审的NCI资金或可资助的优先得分，3人获得第二年的资金，3人获得第二年的资金， 提供的数据，这是为这次更新选定的主要研究项目的工具。的 发展研究计划将提供高达50，000美元的一年（25，000美元从UI/MC孢子 每年向四个项目中的每一个项目提供25，000美元的资金， 根据进展情况提供第二年支助的可能性。预计发展支助 研究项目将继续产生新的假设，这些假设将在完整的UI/MC中进行测试 SPORE赞助的项目或通过同行评审的外部赠款支持。的长期目标 UI/MC SPORE计划是将开发项目产生的发现转化为减少 淋巴瘤的发病率和死亡率。更具体地说， 研究计划是：（1）鼓励创新的实验室，人口和 淋巴瘤和慢性淋巴细胞白血病的临床研究;（2）促进 淋巴瘤转化研究中的基础科学、人口科学和临床学科;以及，（3） 产生新的假设，在大规模的研究项目或临床试验中进行测试，可能导致 显著降低淋巴瘤的发病率和死亡率。四个发展研究的简要概述 来自爱荷华大学和马约诊所的研究人员的项目被包括在内，以证明 正在进行的研究的深度和广度，可以应用于这些转化淋巴瘤研究 机构，并可能有资格获得UI/MC孢子发展计划的支持。

The goal ofthe University of lowa / Mayo Clinic Lymphoma SPORE (UI/MC SPORE) Developmental Research Program is to support innovative, scientifically sound projects that investigate a question pertaining to translational lymphoma research. This program was highly successful with past and current support over the past 4 years going to 13 developmental research projects. Three of these projects have received external, peer-reviewed NCI funding or a fundable priority score, 3 received a second year of funding, and 3 provided data that was instrumental for the major research projects selected for this renewal. The Developmental Research Program will provide up to $50,000 for one year ($25,000 from UI/MC SPORE funds and a matching $25,000 from institutional resources) to each of four projects each year with the possibility of a second year of support based on progress. It is anticipated that support of developmental research projects will continue to result in the generation of new hypotheses that will be tested in full UI/MC SPORE-sponsored projects or through peer reviewed external grant support. The long-term goal of the UI/MC SPORE program is to translate the findings generated by developmental projects into a reduction in the incidence and mortality rates of lymphoma. More specifically, the objectives ef the Developmental Research Program are to: (1) encourage innovative translationally-relevant laboratory, population and clinical studies in lymphoma and chronic lymphocytic leukemia; (2) foster extensive collaboration between basic science, population science and clinical disciplines in translational research in lymphoma; and, (3) generate new hypotheses to be tested in large-scale research projects or clinical trials that may lead to significant reduction of lymphoma incidence and mortality. Brief outlines of four developmental research projects from investigators at the University of lowa and the Mayo Clinic are included to demonstrate the depth and breadth of ongoing research that can be applied to the translational lymphoma research at these institutions and could be eligible for UI/MC SPORE Developmental Program support.