DEVELOPMENTAL RESEARCH PROGRAM

发展研究计划

• 批准号: 8395839
• 负责人: Steven R Lentz
• 金额: $ 16.08万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-11 至 2017-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8395839
• 关键词: Area; Award; Basic Science; Chronic Lymphocytic Leukemia; Clinic; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Collaborations; Commit; Data; Development; Developmental Therapeutics Program; Discipline; Environment; Fostering; Foundations; Funding; Generations; Goals; Grant; Human; Immunology; Incidence; Institution; Laboratories; Laboratory Study; Lead; Lymphoma; Malignant Neoplasms; Patients; Peer Review; Phase; Population Sciences; Population Study; Psychological Techniques; Research; Research Personnel; Research Project Grants; Research Support; Resources; Scientist; Specialized Program of Research Excellence; Testing; Translating; Translational Research; Tumor Biology; Universities; Work; base; innovation; leukemia/lymphoma; mortality; programs; sound

The goal ofthe University of lowa / Mayo Clinic Lymphoma SPORE (UI/MC SPORE) Developmental Research Program is to support innovative, scientifically sound projects that investigate a question pertaining to translational lymphoma research. This program was highly successful with past and current support over the past 4 years going to 13 developmental research projects. Three of these projects have received external, peer-reviewed NCI funding or a fundable priority score, 3 received a second year of funding, and 3 provided data that was instrumental for the major research projects selected for this renewal. The Developmental Research Program will provide up to $50,000 for one year ($25,000 from UI/MC SPORE funds and a matching $25,000 from institutional resources) to each of four projects each year with the possibility of a second year of support based on progress. It is anticipated that support of developmental research projects will continue to result in the generation of new hypotheses that will be tested in full UI/MC SPORE-sponsored projects or through peer reviewed external grant support. The long-term goal of the UI/MC SPORE program is to translate the findings generated by developmental projects into a reduction in the incidence and mortality rates of lymphoma. More specifically, the objectives ef the Developmental Research Program are to: (1) encourage innovative translationally-relevant laboratory, population and clinical studies in lymphoma and chronic lymphocytic leukemia; (2) foster extensive collaboration between basic science, population science and clinical disciplines in translational research in lymphoma; and, (3) generate new hypotheses to be tested in large-scale research projects or clinical trials that may lead to significant reduction of lymphoma incidence and mortality. Brief outlines of four developmental research projects from investigators at the University of lowa and the Mayo Clinic are included to demonstrate the depth and breadth of ongoing research that can be applied to the translational lymphoma research at these institutions and could be eligible for UI/MC SPORE Developmental Program support.

洛瓦大学/梅奥诊所淋巴瘤 SPORE (UI/MC SPORE) 发展目标 研究计划旨在支持创新的、科学合理的项目，以调查相关问题 转化淋巴瘤研究。该计划在过去和当前的支持下非常成功 过去4年进行了13个开发研究项目。其中三个项目已获得 外部、同行评审的 NCI 资助或可资助的优先分数，3 人获得第二年的资助，以及 3 人 提供的数据对于本次更新选定的主要研究项目很有帮助。这 发展研究计划将提供一年高达 50,000 美元的资金（25,000 美元来自 UI/MC SPORE） 资金和来自机构资源的配套 25,000 美元），每年向四个项目中的每一个项目提供 根据进展提供第二年支持的可能性。预计发展支持 研究项目将继续产生新的假设，并在完整的 UI/MC 中进行测试 SPORE 赞助的项目或通过同行评审的外部赠款支持。该组织的长期目标 UI/MC SPORE 计划旨在将开发项目产生的发现转化为减少 淋巴瘤的发病率和死亡率。更具体地说，发展目标 研究计划旨在：(1) 鼓励与转化相关的创新实验室、人群和 淋巴瘤和慢性淋巴细胞白血病的临床研究； （二）促进广泛合作 淋巴瘤转化研究的基础科学、人口科学和临床学科；并且，(3) 产生新的假设，并在大规模研究项目或临床试验中进行测试，这可能会导致 淋巴瘤发病率和死亡率显着降低。四项发展研究概要 洛瓦大学和梅奥诊所的研究人员的项目也被包括在内，以证明 正在进行的研究的深度和广度可应用于这些领域的转化淋巴瘤研究 机构，并可能有资格获得 UI/MC SPORE 发展计划支持。