Interactions between diet, microbiome, genetics and epigentics in determining risk for adenomatous polyps

饮食、微生物组、遗传学和表观遗传学之间的相互作用在确定腺瘤性息肉的风险中

• 批准号: nhmrc : GNT1129430
• 负责人: Dr Emma Beckett
• 金额: $ 31.88万
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/interactions-diet-microbiome-adenomatous-polyps/1347754
• 关键词: Interactions; between; diet; microbiome; genetics

The bacteria that live in the gut interact with the hosts cells and are thought to contribute to causing or preventing diseases, including bowel cancer. We know that diet can change these bacteria populations, but we still do not fully understand how they interact with host cells. The differences in our personal genes are often included in studies of gut bacteria and health and disease. This project aims to consider the role of genes for taste in changing the bacteria and the body’s responses.

生活在肠道中的细菌与宿主细胞相互作用，被认为有助于引起或预防疾病，包括肠癌。我们知道饮食可以改变这些细菌的数量，但我们仍然不完全了解它们如何与宿主细胞相互作用。我们个人基因的差异通常包括在肠道细菌和健康与疾病的研究中。该项目旨在考虑味觉基因在改变细菌和身体反应中的作用。