Interactions between diet, microbiome, genetics and epigentics in determining risk for adenomatous polyps

饮食、微生物组、遗传学和表观遗传学之间的相互作用在确定腺瘤性息肉的风险中

• 批准号: nhmrc : 1129430
• 金额: $ 21.75万
• 依托单位: The University of Newcastle
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/interactions-diet-microbiome-adenomatous-polyps/948403
• 关键词: Interactions; between; diet; microbiome; genetics

The bacteria that live in the gut interact with the hosts cells and are thought to contribute to causing or preventing diseases, including bowel cancer. We know that diet can change these bacteria populations, but we still do not fully understand how they interact with host cells. The differences in our personal genes are often included in studies of gut bacteria and health and disease. This project aims to consider the role of genes for taste in changing the bacteria and the body’s responses.

生活在肠道中的细菌与宿主细胞相互作用，被认为有助于引起或预防包括肠癌在内的疾病。我们知道饮食可以改变这些细菌种群，但我们仍然不完全了解它们如何与宿主细胞相互作用。我们个人基因的差异经常被包括在对肠道细菌、健康和疾病的研究中。该项目旨在考虑味觉基因在改变细菌和人体反应方面的作用。