UNC Center for AIDS Research

北卡罗来纳大学艾滋病研究中心

• 批准号: 8708733
• 负责人: Ronald I Swanstrom
• 金额: $ 315.26万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-20 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8708733
• 关键词: AIDS clinical trial group; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Acute; Advocacy; Affect; Analytical Chemistry; Area; Award; Behavioral; Behavioral Research; Biometry; Biostatistics Core; Central America; China; Clinical; Clinical Pharmacology; Clinical Research; Collaborations; Commit; Communities; Core Facility; Country; Criminal Justice; Data; Databases; Development; Distance Learning; Education and Outreach; Electronics; Epidemic; Epidemiology; Faculty; Family health status; Funding; Goals; HIV; HIV Infections; Health; Health Sciences; Historically Black Colleges and Universities; IMPAACT; Immunology; Individual; Infection; Institutes; Institution; Interdisciplinary Study; International; Laboratories; Leadership; Link; Malawi; Malignant Neoplasms; Newsletter; North Carolina; Online Systems; Pathogenesis; Patients; Play; Prevention; Process; Protocols documentation; Public Health; Publishing; Reporting; Research; Research Activity; Research Infrastructure; Research Personnel; Research Support; Resources; Role; Running; Russia; Sampling; Site; Social Sciences; South Africa; Specimen; Strategic Planning; System; Training; Translational Research; United States National Institutes of Health; Work; base; behavioral/social science; cohort; innovation; intravenous drug user; member; multidisciplinary; outreach; outreach program; programs; repository; response; social science research; tool; virology; working group

The UNC CFAR is a consortium of three Institutions: UNC Chapel Hill, Research Triangle Institute (RTI), and Family Health International (FHl). All three institutions are part of the North Carolina Research Triangle Park, and RTI and FHl have historical links to UNC starting with their inception. The goal of the CFAR is promote the broad sweep of HIV/AIDS research through a variety of mechanisms. The CFAR provides core facilities specifically targeted to the needs of the HIV/AIDS research community. The CFAR Developmental Core supports new research initiatives from junior faculty, faculty new to HIV research, faculty at in-State HBCUs, and researchers at CFAR-linked international sites. The CFAR Developmental Awards program has been expanded by 50% with institutional funds, and this funding is further leveraged in partnership with departments and the CTSA in their developmental awards program. The CFAR sponsors the UNC CFAR HIV Clinical Cohort (UCHCC) database, which plays a central role In managing clinical HIV research activity at UNC, and the UCHCC Is part of the Inter-CFAR CNICS network, with the CNICS Biostatistics and Epidemiology Core now residing at UNC. A major strength of the UNC CFAR is our involvement in international work, with key links to Malawi, South Africa, China, Russia, Central America, and the DRC. These links facilitate international research, capacity building, and provide infrastructure for support of important NIH initiative such as the CHAVI and HPTN. Another important feature of our CFAR is our Clinical Pharmacology and Analytical Chemistry Core, which is unique among CFARs and has become a resource both for other CFARs and for several large NIH initiatives. The CFAR Cores and leadership are supporting four new initiatives: HIV latency and eradication; the IDU epidemic in St. Petersburg, Russia; AIDS malignancies; and HIV and the Criminal Justice System (in partnership with the NC State Department of Corrections). These areas are also supported by working groups, in addition to a long standing working group on Acute HIV Infection (in partnership with the NC State Health Department), and a new working group on Structural Determinants of HIV. The UNC CFAR also engages in a number of outreach programs, including developing a distance-learning program for our In-State HBCUs based on the UNC AIDS Course. In recognition of the importance of the CFAR, we receive significant institutional support including the assignment of space to the CFAR for CFAR investigators. The CFAR has become an essential part of the leadership, infrastructure, and identify of the HIV/AIDS research effort among our membership.

该协会是一个由三个机构组成的联合体：查佩尔山、三角研究所和国际家庭保健组织。这三个机构都是北卡罗来纳州研究三角公园的一部分，RTI和FHl从成立之初就与北卡罗来纳大学有着历史联系。艾滋病毒/艾滋病研究框架的目标是通过各种机制促进广泛的艾滋病毒/艾滋病研究。该中心提供专门针对艾滋病毒/艾滋病研究界需要的核心设施。CFAR发展核心支持初级教师，教师新的艾滋病毒研究，教师在国家HBCUs和CFAR链接的国际网站的研究人员的新的研究计划。CFAR发展奖励计划已扩大了50%的机构资金，并进一步利用这笔资金与各部门和CTSA在其发展奖励计划的伙伴关系。CFAR赞助了CFAR艾滋病毒临床队列（UCHCC）数据库，该数据库在管理临床艾滋病毒研究活动中发挥着核心作用，UCHCC是CFAR间CNICS网络的一部分，CNICS生物统计学和流行病学核心现在位于北京。中非合作论坛的一个主要优势是我们参与国际工作，与马拉维、南非、中国、俄罗斯、中美洲和刚果民主共和国有着重要联系。这些联系促进了国际研究、能力建设，并为支持CHAVI和HPTN等重要NIH倡议提供了基础设施。我们的CFAR的另一个重要特征是我们的临床药理学和分析化学核心，这是CFAR中独一无二的，并已成为其他CFAR和几个大型NIH计划的资源。CFAR核心和领导层正在支持四项新举措：艾滋病毒潜伏和根除;俄罗斯彼得堡的注射吸毒流行病;艾滋病恶性肿瘤;以及艾滋病毒和刑事司法系统（与北卡罗来纳州国家惩教部合作）。这些领域也得到了工作组的支持，此外还有一个长期的急性艾滋病毒感染工作组（与北卡罗来纳州卫生部合作）和一个新的艾滋病毒结构决定因素工作组。该委员会还参与了一些外联方案，包括为我们的州内HBCU制定一个基于艾滋病课程的远程学习方案。由于认识到CFAR的重要性，我们获得了重要的机构支持，包括为CFAR调查人员分配CFAR空间。CFAR已成为我们成员中艾滋病毒/艾滋病研究工作的领导、基础设施和身份的重要组成部分。