Developmental Core

项目总结(见说明)： 发展核心的长期目标是从我们的三个成员机构(FHL、RTI、UNC)以及整个北卡罗来纳州的历史黑人学院和大学(HBCU)以及与UNC、RTI和FHL合作的国际合作伙伴那里筹集和提供资金，用于关注艾滋病毒的新研究项目。我们会进行客观的同行评议，并委派资深调查人员担任导师，以培育 研究及随后的出版和拨款申请。在新的赠款周期的第一年，我们将把CFAR基金的150,000美元和北卡罗来纳大学的75,000美元结合起来，支持艾滋病毒研究(基础和临床科学、转化研究、流行病学、疫苗学和行为研究)各个方面的小额(5,000-20,000美元)奖项。将确定和指导有前途的少数族裔、女性和初级调查人员 直到他们拥有成功的独立事业，包括外部资金。我们将继续把重点放在妇女、少数群体和国际社会目前的流行病上。我们还将在两种情况下提供更大的奖励(最高50,000美元)：源自其中一个工作组的多学科协作努力， 其中包括CFAR的四项举措；以及与CTSA发展核心的合作，其中发放了较大的奖金，但费用与CFAR分担，在某些情况下还与赞助部门分担，从而使CFAR的资金增加了2-4倍。外展和教育将通过以下方式完成：1)所有获奖者在我们每周ID/CFAR会议上发表演讲；2)我们为来自东南部的500名临床医生举办的年度艾滋病毒更新课程；3)在HIV获奖者那里展示海报 更新和世界艾滋病日，以及4)在南非和马拉维举行的研究传播会议。 持续的质量改进将仍然是一个重点，包括对整个过程的审查，包括招标、审查、指导和获奖者的生产力。

PROJECT SUMMARY (See instructions): The long term goals of the Developmental Core are to solicit and provide funding for novel research projects focusing on HIV from our three member institutions (FHl, RTI, UNC) as well as Historically Black Colleges and Universities (HBCUs) throughout North Carolina and international partners working with UNC, RTI, and FHl. We will conduct objective peer review and assign senior investigators as mentors to nurture the research and subsequent publication and grant submission. In the first year ofthe new grant cycle we will combine $150,000 of CFAR funds with $75,000 of UNC funds to support small ($5,000-$20,000) awards in all aspects of HIV research (basic and clinical sciences, translational research, epidemiology, vaccinology, and behavioral research). Promising minority, female and junior investigators will be identified and mentored until they have successful independent careers, including external funding. We will continue to focus on the ongoing epidemic in women, minorities and international communities. We will also make larger awards (up to $50,000) in two settings: collaborative multidisciplinary efforts that originate in one of the Working Groups, which include the four CFAR initiatives; and in collaboration with the Developmental Core of the CTSA in which the larger award is made but the costs are shared with the CFAR and in some cases also the sponsoring Department, thus leveraging CFAR funding 2-4 fold. Outreach and education will be accomplished through: 1) presentation by all awardees at our weekly ID/CFAR conference, 2) our annual HIV Update course for 500 clinicians from the Southeast, 3) presentation of posters by awardees at the HIV Update and World AIDS Day, and 4) Research Dissemination Meetings in South Africa and Malawi. Continuous quality improvement will remain a focus consisting of a review of the entire process including solicitation, review, mentoring and productivity of awardees.