Morehouse Cardiovascular Research Center of Excellence

描述（由申请人提供）：健康方面的种族/民族差异和少数族裔科学家代表性不足的双重问题是生物医学领域面临的两个最引人注目的挑战。少数族裔服务机构 (MSI) 未得到充分利用 作为解决这些棘手问题的一部分。莫尔豪斯医学院 (MSM) 的核心使命是通过教育大量少数族裔学生并培养他们成为科学领导者，扩大国家生物医学劳动力的多样性。 MSM 的社会使命是致力于通过“为服务不足的人服务”来解决健康不平等问题。 MSM 作为 MSI 的独特定位，利用 PSO 奖励机制建立 NHLBI 卓越研究中心，该中心在前沿发现科学、少数族裔健康研究和培训代表性不足的少数族裔研究人员成为下一代科学领导者方面表现出色。 PSO 计划的长期目标与 MSM 的使命非常一致，这引起了行政领导层的强有力的机构承诺。我们的方法旨在通过将 PSO 计划资源集中在我们的三大资产——我们的教师、我们的研究基础设施和我们未来的科学家上，不断增强实力。因此，该 PSO 计划的三个主要目标是： 1) 已向 CVRI 汇报的“新研究者”的保留和职业发展，2) 不断增强我们的共享资源，以及 3) 进一步完善我们针对代表性不足的少数族裔学生的研究培训环境。这些目标将通过追求以下具体目标来实现： 目标一：指导和培养一批有才华的研究人员，使他们成为独立研究项目和跨学科合作研究团队的领导者。 目标二：建立支持尖端心血管科学的支持技术和共享研究基础设施。 目标三：通过维持有利于培训和培育少数族裔学生成为领先研究人员的充满活力的智力环境，扩大生物医学研究界的种族/民族多样性。 目标四：开发创新的跨学科研究项目，整合基础、转化、临床和人口科学方法，以解决心血管健康方面的种族/民族差异。 相关性：生物医学研究界面临的两个最关键的问题是：1）与种族/族裔相关的健康差异问题；2）缺乏少数派科学家。一个关键的解决方案是在少数族裔服务机构中建立研究培训能力，这些机构教育大部分少数族裔学生，并专注于增强少数族裔社区健康的创新转化研究。

DESCRIPTION (provided by applicant): The dual-edged problem of racial/ethnic disparities in health and the under-representation of minority scientists are two of the most compelling challenges facing the field of biomedicine. Minority-Serving Institutions (MSIs) are under-utilized as part of the solution to these vexing problems. The core mission of the Morehouse School of Medicine (MSM) is to expand the diversity of the nation's biomedical workforce by educating a high proportion of under-represented minority students and prepare them to be scientific leaders. MSM's social mission is dedicated to addressing health inequities by 'serving the underserved'. MSM is uniquely positioned as a MSI to utilize this PSO award mechanism to establish a NHLBI Research Center of Excellence that is preeminent in leading-edge discovery science, minority health research and training under-represented minority investigators to emerge as the next generation of scientific leaders. The long-term goals of the PSO Program are well aligned with MSM's mission and this has engendered the strong institutional commitment of the executive leadership. Our approach seeks to build strength upon strength by focusing the PSO program resources on our three major assets ~ our faculty, our research infrastructure and our future scientists. Accordingly, the three major objectives of this PSO program are; 1) the retention and career development of 'new investigators' that have already been recited to the CVRI, 2) the ongoing enhancement of our shared-use resources, and 3) the further refinement of our research training environment for under-represented minority students. These objectives will be achieved by pursuing the following specific aims: Aim I: To mentor and develop a critical mass of talented investigators that emerge as leaders of independent research programs and cross-disciplinary, collaborative research teams. Aim II: To establish enabling technologies and a shared-use research infrastructure that supports leading- edge cardiovascular science. Aim III: To expand the racial/ethnic diversity of the biomedical research community by sustaining a vibrant intellectual environment conducive to training and nurturing the development of minority students into leading investigators. Aim IV: To develop innovative, cross-disciplinary research programs that integrate basic, translational, clinical and population science approaches to address racial/ethnic disparities in cardiovascular health. RELEVANCE: Two of the most critical problems facing the biomedical research community are: 1) the problem of health disparities related to race/ethnicity and 2) the lack of minority scientiss. A key solution is to build research training capacity at minority-serving institutions that educatea large proportion of minority students and are focused on innovative translational research that enhances the health of minority communities.