Enhanced Access to HIV Care for Drug Users in San Juan, Puerto Rico
波多黎各圣胡安吸毒者获得更多艾滋病毒护理
基本信息
- 批准号:8608514
- 负责人:
- 金额:$ 214.4万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-02-01 至 2018-01-31
- 项目状态:已结题
- 来源:
- 关键词:AIDS/HIV problemAddressAdherenceAffectAlcohol or Other Drugs useAlcoholsAnti-Retroviral AgentsAttentionBehavioralBiologicalCaringCommunitiesComorbidityDiagnosisDropsDrug usageDrug userEarly identificationEffectivenessEnsureEnvironmentEpidemicEvaluationFaceFailureFoodGeographic stateGoalsHIVHIV SeropositivityHarm ReductionHealthHealth ServicesHealth Services AccessibilityHuman immunodeficiency virus testImprove AccessIncidenceIndividualInfectionInjecting drug userInjection of therapeutic agentInterdisciplinary StudyInterpersonal ViolenceInterventionKnowledgeLegalLifeLinkMental HealthModelingMorbidity - disease rateNeighborhoodsOutcomePatientsPersonsPharmaceutical PreparationsPopulationPovertyPrimary Health CareProcessPsyche structurePsychiatric Social WorkPublic HealthPuerto RicoQuality of lifeRandomizedRecording of previous eventsResearchScientific Advances and AccomplishmentsServicesStructureSubstance Use DisorderTestingTranslatingTreatment ProtocolsUnited StatesVisitantiretroviral therapycohortcostcost effectivenessdesignhealth care service utilizationhealth inequalitiesheuristicshousing instabilityimmune functionimprovedinjection drug useinnovationmHealthpreventprimary outcomepublic health relevancescreeningsecondary outcomesocialsuccesstherapy adherencetransmission processuptake
项目摘要
DESCRIPTION (provided by applicant): Recent scientific advances demonstrate that for people living with HIV, antiretroviral therapy (ART) is the most effective strategy to improve immune function, reduce morbidity, improve quality of life, prolong survival, and prevent HIV transmission. Translating this knowledge into practice, however, requires prompt diagnosis and linkage to care, entry into care with timely ART initiation, and engagement in care, support for ART adherence, and retention to promote durable virologic suppression. Addressing failures in the implementation of this cascade of care, often referred to as the "Seek, Test, Treat, and Retain (STTR)" paradigm, is vital to achieving the goals of the National HIV/AIDS strategy in the United States. To date, much of the research and discussion surrounding this strategy has focused on expanding HIV testing to improve the early identification of new cases. There has been less attention focused on linkage to, engagement in, and retention in care. Specifically, little attention has focused on identifying HIV-infected individuals who, despite being aware of their diagnosis, have never been in HIV care, are intermittent users of care, or have dropped out of care. A particularly difficult subpopulation to link to and retain in HIV care are HIV-infected drug users. In Puerto Rico, drug use, especially injection drug use, continues to fuel a fast-growing HIV epidemic. Within this context, the overall goal of our proposed project is to implement and evaluate a community-level, structured approach to enhance HIV care access and retention for drug users in San Juan, Puerto Rico. The proposed intervention will be to: 1) identify drug users living with HIV who either do not know their HIV status and/or are not engaged in HIV care; 2) provide direct HIV care services through a mobile health van; and 3) support identified HIV-infected drug users with patient navigators to enhance their ability to engage in HIV care, to initiate antiretroviral therapy, and maintain adherence to their treatment regimens. We are proposing to evaluate our structural enhanced care approach through a randomized roll-out design, a refinement of the stepped-wedge design. The community-level success of the intervention will be assessed by evaluating virologic suppression (primary biological outcome), increased attendance to HIV care visits, uptake of antiretroviral therapy, adherence to HIV treatment regimens, and decreased substance use (as secondary behavioral outcomes) in an independent cohort of HIV-positive individuals drawn from each of the neighborhoods included in the intervention. We will also evaluate the implementation process and cost of the enhanced care approach including implications for cost-effectiveness, feasibility of expansion, and sustainability.
描述(申请人提供):最近的科学进步表明,对于艾滋病毒携带者,抗逆转录病毒疗法(ART)是改善免疫功能、减少发病率、提高生活质量、延长生存时间和防止艾滋病毒传播的最有效策略。然而,将这些知识转化为实践,需要及时诊断和联系护理,及时启动ART进入护理,并参与护理,支持ART的坚持和保留,以促进持久的病毒学抑制。解决这一系列护理(通常被称为“寻求、检测、治疗和保留”(STTR)模式)实施过程中的失败,对于实现美国国家艾滋病毒/艾滋病战略的目标至关重要。到目前为止,围绕这一战略的大部分研究和讨论都集中在扩大艾滋病毒检测以改进新病例的早期识别上。人们对护理的关联、参与和保留的关注较少。具体地说,很少把注意力集中在确定艾滋病毒感染者,尽管他们知道自己的诊断结果,但从未接受过艾滋病毒护理,断断续续地使用护理,或退出护理。在艾滋病毒护理中特别难以联系和留住的一个亚群是艾滋病毒感染吸毒者。在波多黎各,吸毒,特别是注射吸毒,继续助长快速增长的艾滋病毒流行。在这方面,我们拟议项目的总体目标是在波多黎各圣胡安实施和评价一种社区一级的结构化办法,以加强吸毒者获得艾滋病毒护理的机会和留存艾滋病毒的机会。拟议的干预措施将是:1)查明不知道自己的艾滋病毒状况和/或没有从事艾滋病毒护理工作的艾滋病毒携带者;2)通过流动保健车提供直接的艾滋病毒护理服务;3)通过患者导航器支持已确认的艾滋病毒感染者,以增强他们从事艾滋病毒护理、启动抗逆转录病毒疗法和保持遵守其治疗方案的能力。我们建议通过随机推出设计来评估我们的结构性增强护理方法,这是对阶梯式楔形设计的改进。社区层面的干预成功将通过评估病毒学抑制(主要生物学结果)、增加艾滋病毒护理访问的次数、接受抗逆转录病毒治疗、遵守艾滋病毒治疗方案以及减少物质使用(作为次要行为结果)来评估,该队列从干预中包括的每个社区中抽取艾滋病毒阳性个人。我们还将评估加强护理方法的实施过程和成本,包括对成本效益、扩展的可行性和可持续性的影响。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Lisa R Metsch其他文献
Lisa R Metsch的其他文献
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{{ truncateString('Lisa R Metsch', 18)}}的其他基金
Enhanced Access to HIV Care for Drug Users in San Juan, Puerto Rico
波多黎各圣胡安吸毒者获得更多艾滋病毒护理
- 批准号:
8485379 - 财政年份:2013
- 资助金额:
$ 214.4万 - 项目类别:
Enhanced Access to HIV Care for Drug Users in San Juan, Puerto Rico
波多黎各圣胡安吸毒者获得更多艾滋病毒护理
- 批准号:
9012059 - 财政年份:2013
- 资助金额:
$ 214.4万 - 项目类别:
Enhanced Access to HIV Care for Drug Users in San Juan, Puerto Rico
波多黎各圣胡安吸毒者获得更多艾滋病毒护理
- 批准号:
9220770 - 财政年份:2013
- 资助金额:
$ 214.4万 - 项目类别:
Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine Users
RETAIN 项目:为感染艾滋病毒的快克可卡因使用者提供综合护理
- 批准号:
8313066 - 财政年份:2011
- 资助金额:
$ 214.4万 - 项目类别:
Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine Users
RETAIN 项目:为感染艾滋病毒的快克可卡因使用者提供综合护理
- 批准号:
8517243 - 财政年份:2011
- 资助金额:
$ 214.4万 - 项目类别:
Behavioral/Social Sciences & Community Outreach Core (BSSCOC)
行为/社会科学
- 批准号:
8288874 - 财政年份:2011
- 资助金额:
$ 214.4万 - 项目类别:
Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine Users
RETAIN 项目:为感染艾滋病毒的快克可卡因使用者提供综合护理
- 批准号:
8190910 - 财政年份:2011
- 资助金额:
$ 214.4万 - 项目类别:
Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine Users
RETAIN 项目:为感染艾滋病毒的快克可卡因使用者提供综合护理
- 批准号:
8727903 - 财政年份:2011
- 资助金额:
$ 214.4万 - 项目类别:
Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine Users
RETAIN 项目:为感染艾滋病毒的快克可卡因使用者提供综合护理
- 批准号:
8653837 - 财政年份:2011
- 资助金额:
$ 214.4万 - 项目类别:
Project RETAIN: Providing Integrated Care for HIV-Infected Crack Cocaine Users
RETAIN 项目:为感染艾滋病毒的快克可卡因使用者提供综合护理
- 批准号:
8452137 - 财政年份:2011
- 资助金额:
$ 214.4万 - 项目类别:
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