IGF::OT::IGF OMICS IN LATINOS - GENETIC ANALYSIS (OLGA)

拉丁美洲人的 IGF::OT::IGF 组学 - 遗传分析 (OLGA)

• 批准号: 8926495
• 负责人: Bruce S. Weir
• 金额: $ 29.41万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2015-12-08
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8926495
• 关键词: Age; Centers for Disease Control and Prevention (U.S.); Contractor; Dental Hygiene; Dental caries; Diabetes Mellitus; Ethnic Origin; Gender; Intake; Latino; Manuscripts; Measures; Paper; Periodontal Diseases; Preparation; Race; Risk Factors; Tobacco use; base; gene environment interaction; genetic analysis; genome wide association study; sugar; working group

Examine: 1) Genome-wide association analysis for periodontal disease, including covariates such as age, gender, and race/ethnicity; papers proposals generated by HCHS/SOL working groups; 2) Gene-environment interaction in periodontal disease for 2-3 established risk factors, such as tobacco use and diabetes; 3) Genome-wide association analysis for dental caries, including covariates such as age, gender and race/ethnicity, and 4) Gene-environment interaction in dental caries for 2-3 established risk factors such as sugar intake or oral hygiene practices.

检查：1）牙周病的全基因组关联分析，包括协变量，如年龄，性别和种族/民族; HCHS/SOL工作组产生的论文提案; 2）牙周病中2-3个已确定的风险因素的基因-环境相互作用，如烟草使用和糖尿病; 3）龋齿的全基因组关联分析，包括协变量如年龄、性别和种族/民族，（4）龋病的基因-环境交互作用，包括2-3个确定的危险因素，如糖摄入量或口腔卫生习惯。