Investigating the interplay between post-transcriptional and post-translational regulation of insulin resistance

研究胰岛素抵抗的转录后和翻译后调节之间的相互作用

• 批准号: nhmrc : 1072129
• 负责人: Dr Benjamin Parker
• 金额: $ 21.1万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigating-interplay-post-insulin-resistance/455493
• 关键词: Investigating; interplay; between; post; transcriptional

Insulin resistance or reduced ability of cells to respond to insulin and is a major contributor to type-2 diabetes (T2D). More than 1.7 million Australians are currently diagnosed with T2D and this is projected to double in the next ten years. The cause of insulin resistance is unknown. This application will integrate two novel innovative scientific techniques to unravel the mechanisms of IR.

胰岛素抵抗或细胞对胰岛素反应的能力降低，是导致 2 型糖尿病 (T2D) 的主要原因。目前有超过 170 万澳大利亚人被诊断患有 T2D，预计未来十年这一数字将翻一番。胰岛素抵抗的原因尚不清楚。该应用程序将整合两种新颖的创新科学技术来揭示红外线的机制。