Sedative-hypnotic use in US older adults: Recent trends and associated outcomes

美国老年人使用镇静催眠药：最新趋势和相关结果

• 批准号: 8716517
• 负责人: Christopher Norfleet Kaufmann
• 金额: $ 4.07万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-20 至 2015-07-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8716517
• 关键词: Address; Adverse effects; Affect; Anxiety; Awareness; Beer; Benzodiazepines; Biometry; Clinical; Clinical Trials; Complement; Data; Development; Disincentive; Drug Insurance; Drug Prescriptions; Effectiveness; Elderly; Epidemiology; Eszopiclone; Exclusion; Fellowship; Formularies; Future; Gerontology; Goals; Guidelines; Health; Health Policy; Health Services; Hip Fractures; Hospitalization; Impaired cognition; Insurance; Internal Medicine; Internist; Knowledge; Label; Laws; Light; Medicare; Mentorship; National Ambulatory Medical Care Survey; Nursing Homes; Outcome; Patients; Pattern; Personal Satisfaction; Pharmaceutical Preparations; Physicians; Policies; Population; Population Characteristics; Principal Investigator; Psychiatrist; Psychiatry; Psychologist; Public Health; Publishing; Research; Research Methodology; Research Personnel; Research Project Grants; Retirement; Risk; Sampling; Side; Sleep; Sleep disturbances; Staging; Statistical Methods; Subgroup; Time; Training; Training Programs; Zaleplon; adverse outcome; beneficiary; career; experience; falls; functional decline; functional disability; functional outcomes; health care service utilization; health economics; hypnotic; improved; mortality; population based; professor; programs; prospective; public health relevance; sedative; service utilization; skills; trend; zolpidem

DESCRIPTION (provided by applicant): The goal of this fellowship is to prepare the applicant, Christopher Kaufmann, for an academic research career in geriatric pharmaco-epidemiology, focusing on issues related to [prescribing trends of psychiatric medication to older adults,] and associated health, economic, and societal outcomes. The proposed fellowship consists of two complementary components: a) a research project examining recent trends in the use of sedative-hypnotic medications among older adults, and associated health outcomes and health service utilization in this population; and b) a training plan comprised of formal coursework and mentorship, and other didactic and professional development activities. In the proposed research project, we will examine recent trends in the prescription of sedative-hypnotic medications to older adults, in the context of recent clinical and policy initiatives tackling inappropriate prescription of these medications in this population. [More specifically, we will explore changes in physician prescribing patterns of these medications and patient outcomes in light of the recent introduction of non-benzodiazepine sleep-aid medications and the implementation of Medicare Part D in 2006. We will use data from the National Ambulatory Medical Care Survey (NAMCS) to study physician prescribing trends, and the Health and Retirement Study (HRS) to study the association between sedative- hypnotic use and both adverse health outcomes and service utilization in older adults. This project is supported by a strong interdisciplinary mentorship team with expertise in gerontology, clinical psychiatry, internal medicine, health policy, and statistical methods. Associate Professor Ramin Mojtabai, a practicing psychiatrist with expertise in the pharmaco-epidemiology of psychiatric medications, Professor Joseph Gallo, an established gerontology researcher with extensive mentorship experience, and Assistant Professor Adam Spira, a clinical psychologist with expertise in functional outcomes of late life sleep-disturbances and in anxiety in older adults, will serve as the sponsors of this application. Their mentorship will be complemented by that of Associate Professor Caleb Alexander, an internist with expertise in pharmaco-epidemiology in the Department of Epidemiology, Professor Karen Bandeen-Roche, a statistician with expertise in gerontology in the Department of Biostatistics, and Assistant Professor Lainie Rutkow, from the Department of Health Policy and Management who has expertise in public health law and policy.] The research project and the complementary training plan will provide the applicant with hands-on experience applying pharmaco-epidemiological research methods to answer health-related questions of great relevance to the growing population of older adults. Further, the proposed fellowship will provide Mr. Kaufmann with the skills that he requires to move on to the next stage of his career as an independent researcher.

描述（由申请人提供）：该奖学金的目的是为申请人克里斯托弗·考夫曼（Christopher Kaufmann）做好准备，以使老年医学药物学术学的学术研究生涯，重点介绍了与[处方针对老年人的精神药物趋势的问题]以及相关的健康，经济，经济，社会和社会的成果。拟议的奖学金由两个互补组成部分组成：a）研究项目，研究了老年人使用镇静催眠药的最新趋势，以及该人群中相关的健康结果和健康服务的利用； b）由正式课程和指导以及其他教学和专业发展活动组成的培训计划。在拟议的研究项目中，我们将在最近的临床和政策举措中，在该人群中处理这些药物不适当处方的情况下，我们将研究镇静性催眠药处方的最新趋势。 [More specifically, we will explore changes in physician prescribing patterns of these medications and patient outcomes in light of the recent introduction of non-benzodiazepine sleep-aid medications and the implementation of Medicare Part D in 2006. We will use data from the National Ambulatory Medical Care Survey (NAMCS) to study physician prescribing trends, and the Health and Retirement Study (HRS) to study the association between sedative- hypnotic use and老年人的不良健康结果和服务利用。该项目得到了一个强大的跨学科指导团队的支持，该团队在老年病，临床精神病学，内科，卫生政策和统计方法方面具有专业知识。副教授拉明·莫伊塔巴（Ramin Mojtabai）是一位从事精神病药物药物学专业知识的精神科医生，具有丰富的指导经验的老年医学研究员约瑟夫·加洛（Joseph Gallo）教授，助理教授Adam Spira，助理教授Adam Spira，一位在较晚的生活中，具有临床成员的临床精神知识，并在较晚的生活中，适用于焦点，并在较早的生活中，在这种情况下，在焦点中，在这种情况下，在这种情况下，在这种情况下，在这种生活中，曾在这种生活中，曾在这种生活中及时努力。 Their mentorship will be complemented by that of Associate Professor Caleb Alexander, an internist with expertise in pharmaco-epidemiology in the Department of Epidemiology, Professor Karen Bandeen-Roche, a statistician with expertise in gerontology in the Department of Biostatistics, and Assistant Professor Lainie Rutkow, from the Department of Health Policy and Management who has expertise in public health law and policy.] The research project and互补的培训计划将为申请人提供实践经验，该经验采用药物流行病学研究方法，以回答与健康相关的健康问题，与不断增长的老年人人口有关。此外，拟议的奖学金将为考夫曼先生提供他所需的技能，以至于他作为独立研究员的下一阶段所需的技能。