Decision Making and Dysregulation Pathways in Adolescents with Parental SUD Histo

父母 SUD 史青少年的决策和失调途径

• 批准号: 8669958
• 负责人: Joshua Weller
• 金额: $ 24.6万
• 依托单位: DECISION RESEARCH
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-06-15 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8669958
• 关键词: Address; Adherence; Adolescence; Adolescent; Adult; Affective; Age; Alcohol or Other Drugs use; Behavior; Behavioral; Characteristics; Child; Childhood; Cognitive; Collection; Competence; Data; Data Analyses; Data Set; Decision Making; Development; Diagnosis; Disease; Drug usage; Family; Future; Growth; HIV risk; Health; Health Care Costs; Incidence; Individual; Individual Differences; Informal Social Control; Intervention; Interview; Laboratories; Life; Link; Marijuana Smoking; Measurement; Measures; Mediating; Modeling; Outcome; Parenting behavior; Parents; Participant; Pathway interactions; Pattern; Population; Process; Psychopathology; Public Health; Regulation; Reporting; Research; Research Personnel; Risk; Risk Behaviors; Risk-Taking; Sampling; Sex Behavior; Sexual Partners; Structure; Substance abuse problem; Testing; Time; United States National Institutes of Health; Visit; Work; Youth; anti social; base; criminal behavior; design; disorder risk; drug abuse education; emerging adult; emerging adulthood; follow-up; high risk; high risk sexual behavior; insight; interpartner violence; intimate partner violence; neuropsychological; preadolescence; psychologic; public health relevance; sex risk; skills; social

DESCRIPTION (provided by applicant): Children with a parent diagnosed with substance abuse disorder (SUD) show increased risk for greater drug use, delinquency, and their engagement in health-risking sexual behavior, suggesting maladaptive choice processes with great social and public-health costs (e.g., Kirisci et al., 2007; Reynolds et al., 2007; Tarter et l., 2002). Little is known, however, about the mechanisms that underlie the decisions to engage in these behaviors. We propose to conduct hypothesis-driven secondary data analyses to test a conceptual model that links parental SUD and childhood dysregulation to the development of poor decision-making skills and increased incidence of health-risking behaviors later in life. We will leverage data collected through the Center for Education and Drug Abuse Research (CEDAR; NIH# 5P50 DA05605), using its unique longitudinal dataset that includes validated measures of transmissible liability for SUD risk (Kirisci et al., 2009; Vanyukov et al., 2009), a battery of laboratory-based measures of decision-making competence (DMC; Parker & Fischhoff, 2005), and adult assessments of substance abuse, antisocial behaviors, and sexual behavior. We intend to address five main research questions in the proposed project. First, we plan to identify classes of developmental trajectories for psychological regulation. We will conduct analyses to characterize different patterns of intra-individual change in psychological regulation from preadolescence to emerging adulthood. Second, we plan to refine the measurement of DMC, which can be defined as adherence to normative, rational standards when making decisions (Parker & Fischhoff, 2005) by expanding the construct to encompass excessive risk-taking and insensitivity to expected value. Third, we will examine the associations between family and parenting variables on subsequent DMC and health-risking outcomes later in life. Fourth, we will examine the effects of developmental trajectories of psychological regulation on DMC. While research has linked self-regulative processes to advantageous decision making, such studies have largely relied on cross-sectional designs, and are thus silent on the progression from development of self-regulation to adolescent decision making. Finally, we will test the extent to which poor DMC can predict future health-risking behaviors, such as drug use, criminal behavior, high-risk sexual behavior, and inter-partner violence.

描述（由申请人提供）：父母被诊断为药物滥用障碍（SUD）的儿童表现出更大的药物使用、犯罪和从事危害健康的性行为的风险，表明适应不良的选择过程具有巨大的社会和公共卫生成本（例如，Kirisci等人，2007；Reynolds等人，2007；Tarter等人，2002）。然而，人们对参与这些行为的决定背后的机制知之甚少。我们建议进行假设驱动的二次数据分析，以检验一个概念模型，该模型将父母的SUD和儿童失调与不良决策技能的发展和晚年健康风险行为的发生率增加联系起来。我们将利用教育和药物滥用研究中心（CEDAR; NIH# 5P50 DA05605）收集的数据，使用其独特的纵向数据集，包括SUD风险传播责任的有效测量（Kirisci等人，2009；Vanyukov等人，2009），一系列基于实验室的决策能力测量（DMC; Parker & Fischhoff, 2005），以及药物滥用，反社会行为和性行为的成人评估。我们打算在提议的项目中解决五个主要的研究问题。首先，我们计划确定心理调节的发展轨迹类别。我们将进行分析，以表征从青春期前到成年初期心理调节的不同个体内部变化模式。其次，我们计划完善DMC的测量，DMC可以被定义为在做出决策时遵守规范、理性的标准（Parker & Fischhoff, 2005），通过扩展结构来涵盖过度冒险和对期望值的不敏感。第三，我们将研究家庭和养育变量在随后的DMC和以后生活中健康风险结果之间的关系。第四，研究心理调节发展轨迹对DMC的影响。虽然研究将自我调节过程与有利的决策联系起来，但这些研究在很大程度上依赖于横断面设计，因此对从自我调节发展到青少年决策的进展保持沉默。最后，我们将测试不良DMC在多大程度上可以预测未来的健康风险行为，如吸毒、犯罪行为、高风险性行为和伴侣间暴力。