Investigating post-transcriptional gene regulation in cancer

研究癌症转录后基因调控

• 批准号: nhmrc : 1196405
• 金额: $ 64.52万
• 依托单位国家: 澳大利亚
• 项目类别: Investigator Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2025-12-31
• 项目状态: 未结题
• 来源: https://researchdata.edu.au/investigating-post-transcriptional-regulation-cancer/1779132
• 关键词: Investigating; post; transcriptional; gene; regulation

In this program, I will enhance our understanding of cancer gene regulation and provide novel avenues for the treatment of aggressive tumours. Using own data and that from collaborators, I will determine patterns of gene regulation in blood cancers and identify markers that predict disease outcome. I aim to understand how gene regulation can transform healthy cells into tumour cells and whether personalised treatment can kill tumour cells more effectively and prevent relapse and metastasis.

在这个项目中，我将加强我们对癌症基因调控的理解，并为侵袭性肿瘤的治疗提供新的途径。利用自己和合作者的数据，我将确定血癌中基因调控的模式，并确定预测疾病结果的标记。我的目标是了解基因调控如何将健康细胞转化为肿瘤细胞，以及个性化治疗是否可以更有效地杀死肿瘤细胞并防止复发和转移。