An Internet Based Walking Program for Patients with Peripheral Arterial Disease

针对周围动脉疾病患者的基于互联网的步行计划

• 批准号: 8438563
• 负责人: Elizabeth A. Jackson
• 金额: $ 45.67万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-15 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8438563
• 关键词: Activities of Daily Living; Address; Adherence; Adult; Aging; American; Blood Vessels; Cardiovascular system; Chronic; Climacteric; Clinical Trials Design; Communities; Complex; Coronary Arteriosclerosis; Data; Diabetes Mellitus; Effectiveness; Event; Exercise; Frequencies; Goals; Internet; Intervention; Lower Extremity; Maintenance; Mediating; Medical; Methods; Morbidity - disease rate; Operative Surgical Procedures; Participant; Patients; Peripheral; Peripheral arterial disease; Phase; Physical Function; Physical activity; Population; Randomized; Randomized Controlled Trials; Research Design; Risk; Structure; Symptoms; Testing; Time; Vascular Diseases; Walking; Work; arm; base; claudication; cost; disorder risk; health related quality of life; high risk; improved; intervention program; lifestyle intervention; meetings; member; mortality; programs; public health relevance; social; web site

DESCRIPTION (provided by applicant): With the aging of the American population, the numbers of adults with peripheral arterial disease (PAD) will increase significantly over the next several decades. Patients with PAD are at increased risk for morbidity and mortality including both cardiovascular and all cause mortality. While regular physical activity reduces risk for vascular events and is recommended for treatment of PAD patients, few patients meet recommended goals. Exercise programs which increase long-term adherence to walking be an important contribution to PAD treatment. Our internet-based intervention, with an online community builds on a walking enhancement program develop by members of our team and shown to improve adherence among patients with vascular disease such as patients with coronary artery disease (CAD). Using a randomized, controlled trial study design, we propose to test an automated internet-mediated walking program with a social media component, to improving long-term adherence to walking while increasing walking distance, and health-related quality of life (HRQOL), among patients with PAD. Subjects will be randomized to a supervised walking program, supervised walking with an additional online walking intervention or an online walking intervention alone. This internet based walking intervention with a social media component has been shown to increase both adherence to walking and overall walking duration in populations with chronic complex conditions such as coronary artery disease and diabetes. There is a strong need to develop interventions, easily generalizable to a real-world population, to improve the reach of lifestyle interventions which result in improved physical function and adherence to regular exercise among complex medical patients. High risk patients such as those with PAD (a CAD risk equivalent) stand the most to benefit from such programs.

描述（由申请人提供）：随着美国人口老龄化，患有外周动脉疾病（PAD）的成年人数量将在未来几十年内显着增加。 PAD 患者的发病和死亡风险增加，包括心血管死亡和全因死亡。虽然定期的体力活动可以降低血管事件的风险，并被推荐用于 PAD 患者的治疗，但很少有患者能够达到建议的目标。增加长期步行坚持的锻炼计划对 PAD 治疗有重要贡献。我们基于互联网的干预措施和在线社区建立在我们团队成员开发的步行增强计划的基础上，该计划被证明可以提高冠状动脉疾病 (CAD) 等血管疾病患者的依从性。使用随机对照试验研究设计，我们建议测试带有社交媒体成分的自动化互联网介导的步行计划，以提高 PAD 患者的长期步行依从性，同时增加步行距离和健康相关的生活质量 (HRQOL)。受试者将被随机分配到监督步行计划、监督步行加上额外的在线步行干预或单独的在线步行干预。这种基于互联网的步行干预与社交媒体成分已被证明可以增加患有冠状动脉疾病和糖尿病等慢性复杂疾病的人群对步行的坚持和总体步行时间。迫切需要开发易于推广到现实世界人群的干预措施，以提高生活方式干预的范围，从而改善复杂疾病患者的身体功能并坚持定期锻炼。高风险患者，例如患有 PAD（相当于 CAD 风险）的患者，最能从此类计划中受益。