Investigating the role of TGF-beta in resident memory T cell induction and maintenance

研究 TGF-β 在常驻记忆 T 细胞诱导和维持中的作用

• 批准号: nhmrc : 1038719
• 负责人: Mr Nicholas Collins
• 金额: $ 6.17万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/investigating-role-tgf-induction-maintenance/111206
• 关键词: Investigating; role; TGF; beta; resident

I am a research scientist interested in the immune system. Specifically, I intend to investigate immunological memory, which is the basis of vaccination. This refers to the ability of certain immune cells such as T and B cells to ‘remember’ a pathogen, so that a rapid and enhanced response can be generated upon re-infection with the same pathogen. This can be investigated by experimental techniques such as flow cytometry, histology and confocal microscopy on cells from infected mouse tissue.

我是一名对免疫系统感兴趣的研究科学家。具体来说，我打算研究免疫记忆，这是疫苗接种的基础。这是指某些免疫细胞（例如T细胞和B细胞）“记住”病原体的能力，以便在再次感染相同病原体时可以产生快速且增强的反应。这可以通过流式细胞术、组织学和共聚焦显微镜等实验技术对受感染小鼠组织的细胞进行研究。