研究 FTY720 对非洲人类锥虫病的治疗潜力-猫眼课题宝

研究 FTY720 对非洲人类锥虫病的治疗潜力

批准号：

nhmrc : 1067728

负责人：

Dr Graeme Stevenson

金额：

$43.59万

依托单位：

Griffith University

依托单位国家：

澳大利亚

项目类别：

Project Grants

财政年份：

2014

资助国家：

澳大利亚

项目状态：

已结题

起止时间：

2014-01-01 至 2017-12-31

来源：

https://researchdata.edu.au/investigating-therapeutic-potential-african-trypanosomiasis/455321

关键词：

Investigating therapeutic potential FTY720 Human

中文摘要

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英文摘要

FTY720, is a drug currently used to treat multiple sclerosis, which we have shown is also be able to kill the parasite responsible for African sleeping sickness, Trypanosomes. We aim to identify the target the drug acts on in the parasite to have its affect. Our objective is to improve the activity further by chemical modification to produce a potent, orally available and well characterised, non-toxic drug suitable for preclinical development.

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