Tampa Bay Adolescent Medicine Trial Unit

坦帕湾青少年医学试验中心

• 批准号: 8841601
• 负责人: PATRICIA J EMMANUEL
• 金额: $ 43.61万
• 依托单位: UNIVERSITY OF SOUTH FLORIDA
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-15 至 2017-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8841601
• 关键词: AIDS prevention; Address; Adolescent; Adolescent Medicine; Adolescent and Young Adult; Adult; Aging; Anti-Retroviral Agents; Area; Behavioral Research; Behavioral trial; Caring; Childhood; Clinic; Clinical Services; Clinical Trials; Collaborations; Color; Communities; Community Health; Comprehensive Health Care; Computerized Medical Record; County; Data Quality; Databases; Education; Enrollment; Ensure; Environment; Epidemic; Family health status; Florida; Funding Agency; Grant; HIV; HIV-infected adolescents; Health; Health Services Research; Immune response; Immunology; Incidence; Institution; Interdisciplinary Study; Knowledge; Laboratories; Leadership; Link; Mental Health; Mental Health Services; Minority; Modeling; Newly Diagnosed; Operations Research; Patients; Pediatric Hospitals; Population; Prevention; Prevention education; Principal Investigator; Process; Program Development; Protocols documentation; Psychiatry; Psychology; Public Health; Quality of life; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Research Subjects; Risk; Schools; Services; Sexuality; Students; Testing; Therapeutic Trials; Universities; Vaccine Research; Viral; Woman; Work; Youth; base; clinical infrastructure; cohort; design; improved; innovation; male; medical specialties; men; microbicide; multidisciplinary; outreach; patient population; prevention service; programs; racial and ethnic; research study; sex; translational study; university student; young adult; young men who have sex with men

DESCRIPTION (provided by applicant): The University of South Florida, Tampa Bay Adolescent Trials Unity (TB AMTU) provides primary and specialty care, prevention services and access to clinical trials to HIV infected and at-risk youth in the Tampa Bay area. To sustain and expand these services, the TB AMTU proposes the following specific aims for this proposal: 1) Engage, enroll and retain HIV-infected youth in care and research through a mature clinical and research infrastructure and innovative programs which adapt to the changes in the HIV epidemic, 2) Mobilize and connect the Tampa Bay community in an innovative collaborative effort to address the challenges of the HIV epidemic in youth and young adults, 3) Contribute to the national adolescent HIV agenda by drawing on the strengths of the university environment and an interdisciplinary research network that participates on the design and execution of ATN protocols and engages and supports new investigators. The objectives established support these aims. It is the intent of the TB AMTU to continue to provide a seamless continuum of comprehensive care, address the mental health needs of those served, and support the emerging autonomy of HIV infected youth. The TB AMTU will collaborate with the ATN leadership group to develop clinical trials that address primary, secondary and tertiary HIV prevention and expand services that allow for the implementation of this broad research agenda. To support these efforts, the TB AMTU will continue to build community capacity and enhance successful relationships with its Connect to Protect Partners in executing structural change objectives. New initiatives will include stronger linkage to care processes, enhanced referral networks for Young Men who have Sex with Men (YMSM) and the implementation of a specialty clinic for GLBTQ and other alternative youth. RELEVANCE: The TB AMTU responds to the national public health agenda that emphasize the need to address the disproportionate impact of HIV on minority populations by supporting efforts to engage, recruit and retain youth of racial/ethnic and other minority populations. The unit proactively works to reduce the incidence of HIV in these populations and improve the quality of life for those already infected.

描述(由申请人提供)：南佛罗里达大学坦帕湾青少年试验联合(TB AMTU)为坦帕湾地区感染艾滋病毒的青少年和高危青少年提供初级和专科护理、预防服务和临床试验。为了持续和扩大这些服务，结核病AMTU为这项建议提出了以下具体目标：1)通过成熟的临床和研究基础设施以及适应艾滋病毒流行变化的创新计划，吸引、招收和留住艾滋病毒感染青年参与护理和研究；2)动员坦帕湾社区并将其联系起来，以创新的合作努力应对青年和年轻人中艾滋病毒流行的挑战；3)利用大学环境和跨学科研究网络的优势，为国家青少年艾滋病毒议程做出贡献，该网络参与ATN方案的设计和执行，并吸引和支持新的调查人员。确立的目标支持这些目标。结核病协会的意图是继续提供无缝连续的全面护理，满足受助者的心理健康需求，并支持感染艾滋病毒的青年逐渐获得自主性。结核病AMTU将与ATN领导小组合作，开发针对一级、二级和三级艾滋病毒预防的临床试验，并扩大服务，以便实施这一广泛的研究议程。为支持这些努力，TB AMTU将继续建设社区能力，并加强与其Connect to Protected合作伙伴在执行结构变化目标方面的成功关系。新的举措将包括加强与护理过程的联系，加强针对有男男性行为的青年男子(YMSM)的转介网络，并为GLBTQ和其他替代青年实施专门诊所。 相关性：结核病协会对国家公共卫生议程作出回应，强调需要通过支持努力吸引、招募和留住种族/族裔和其他少数群体的青年，来解决艾滋病毒对少数群体的不成比例的影响。该股积极努力减少这些人群中艾滋病毒的发病率，并改善那些已经感染的人的生活质量。

项目成果

Genetic associations with 25-hydroxyvitamin D deficiency in HIV-1-infected youth: fine-mapping for the GC/DBP gene that encodes the vitamin D-binding protein.

HIV-1 感染青少年中 25-羟基维生素 D 缺乏的遗传关联：编码维生素 D 结合蛋白的 GC/DBP 基因的精细定位。

• DOI: 10.3389/fgene.2013.00234
• 发表时间: 2013
• 期刊: Frontiers in genetics
• 影响因子: 3.7
• 作者: Porter,TravisR;Li,Xuelin;Stephensen,CharlesB;Mulligan,Kathleen;Rutledge,Brandy;Flynn,PatriciaM;Lujan-Zilbermann,Jorge;Hazra,Rohan;Wilson,CraigM;Havens,PeterL;Tang,Jianming;AdolescentMedicineTrialsNetworkforHIV/AIDSIntervent
• 通讯作者: AdolescentMedicineTrialsNetworkforHIV/AIDSIntervent