Systems Science Center for Musculoskeletal CAM Therapies

肌肉骨骼 CAM 治疗系统科学中心

• 批准号: 8937479
• 负责人: Jacek Cholewicki
• 金额: $ 6.69万
• 依托单位: MICHIGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-30 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8937479
• 关键词: Address; Adverse effects; Affect; Award; Awareness; Clinical; Clinical Research; Communities; Devices; Disease; Engineering; Equilibrium; Event; Experimental Designs; Faculty; Future; Genetic Crossing Over; Goals; Head and neck structure; Health Care Costs; Individual; Interdisciplinary Study; Intervention; Leadership; Low Back Pain; Measures; Mentors; Michigan; Motor; Musculoskeletal; Musculoskeletal Equilibrium; Musculoskeletal System; Neck Pain; Nursing Faculty; Osteopathic Medicine; Osteopathic manipulation; Outcome Measure; Patients; Performance; Positioning Attribute; Research; Research Project Grants; Research Training; Resources; Robot; Science; Sensory; Speed; Spinal; Students; System; Therapeutic Studies; Time; United States National Institutes of Health; Universities; base; college; instrument; motor control; multidisciplinary; neuromuscular; neuromusculoskeletal; programs; response; tool

The overall goal of this PCCTR is to address three major barriers to increase capacity for CAM research at Michigan State University College of Osteopathic Medicine (MSUCOM): 1) the lack of standardized, objective instruments and measures for characterizing and optimizing osteopathic manipulative therapy (OMT) interventions, 2) the lack of visible ongoing OMT research programs and 3) the lack of research training of clinical faculty. The rationale for the three research projects is based on the overall hypothesis that OMT affects some aspects of sensory and/or motor functions of the musculoskeletal system. Thus, improvement in performance of such a system should serve as an objective outcome measure. In project one, a systems science approach will be applied to identify deficits in postural control of individuals with low back pain (LBP) and assess the effects of OMT on postural control. A parallel robot device, programmed to mimic unstable sitting on a half-cylinder, will be used to quantify balance and postural control before and after 4 weeks of OMT in a cross-over experimental design. Project two will investigate whether OMT can mitigate adverse effects from a sudden, unexpected trunk perturbation by resulting in a faster and more accurate response of the postural control system to such an event in patients in LBP. The speed of the control system and its accuracy will be quantified before and after 4 weeks of OMT in a cross-over experimental design. Project three will develop clinical research tools for the assessment of motor control of the head-neck system. Using a cross-over experimental design, these tools will then be applied to measure changes in position and force control of the head-neck system in patients with and without neck pain before and after 4 weeks of OMT.

该PCCTR的总体目的是解决密歇根州立大学骨质疗法医学学院（MSUCOM）的三个主要障碍：1）缺乏表征和优化骨质疗法手动治疗（OMT）干预措施的标准化，客观工具和措施，缺乏可见的OMT研究计划和3）研究计划。 这三个研究项目的基本原理是基于总体假设，即OMT会影响肌肉骨骼系统的感觉和/或运动功能的某些方面。 因此，这种系统的性能的改善应作为客观结果指标。 在项目第一中，将采用系统科学方法来确定腰痛（LBP）个体的姿势控制缺陷，并评估OMT对姿势控制的影响。 在半缸上编程的平行机器人设备将用于模仿不稳定的机器人，将用于量化在交叉实验设计中OMT之前和之后的平衡和姿势控制。 项目第二将研究OMT是否可以通过突然的，意外的树干扰动来减轻不良影响，从而导致姿势控制系统对LBP患者的这种事件的更快，更准确的反应。 在交叉实验设计中，将在OMT之前和之后量化控制系统的速度及其精度。 第三项目将开发用于评估头颈系统运动控制的临床研究工具。 然后，使用交叉的实验设计，这些工具将用于测量在OMT 4周之前和之后患有和没有颈部疼痛的患者头颈系统的位置变化和力控制。