Structure-Function Relationship of Glycosaminoglycans

糖胺聚糖的结构-功能关系

• 批准号: 8821745
• 负责人: RAM SASISEKHARAN
• 金额: $ 39万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8821745
• 关键词: Address; Biological Process; Disasters; Glycobiology; Glycosaminoglycans; Heparin; Instruction; Laboratories; Polysaccharides; Proteins; Public Health; Structure-Activity Relationship; tool

The Sasisekharan laboratory focuses on developing tools to study glycan-protein interactions. The laboratory has focused on using these tools to not only instigate the fundamentals of glycans in terms of how they impact biological processes, but they have also harnessed the mechanisms to address important public health crises including the contamination of heparin disaster. The tools developed have implications beyond glycobiology. RELEVANCE (See instructions):

Sasisekharan实验室专注于开发研究糖蛋白相互作用的工具。实验室 专注于使用这些工具不仅在以下方面激发了多糖的基本原理： 影响生物过程，但他们也利用这些机制来解决重要的公众 健康危机，包括肝素污染灾难。开发的工具具有更多的影响 糖生物学。 相关性(请参阅说明)：